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Description Entry page for Effector - 'Adenylate cyclase 4-Homo sapiens'
FamilyCyclases
Sub-FamilyAdenylate cyclases
TypeAdenylate cyclase 4
Cross References:
References
UniProtQ8NFM4 | Q17R40 | Q96ML7
EMBLAF497516 | BC117473 | BC117475 | AK056745
InterProIPR001054 | IPR018297 | IPR009398
PRODOM
GENEID196883
MIM600292
PRINTS
PFAMPF06327 | PF00211
Details:
Details
NameAdenylate cyclase 4-Homo sapiens
DescriptionRecName: Full=Adenylate cyclase type 4; EC=4.6.1.1;AltName: Full=Adenylate cyclase type IV;AltName: Full=ATP pyrophosphate-lyase 4;AltName: Full=Adenylyl cyclase 4
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneADCY
FunctionThis is a membrane-bound, calmodulin-insensitives adenylyl cyclase (By similarity)
Fragment0
Sequence
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLAVAWASGRELTSDPS
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHAFLFTGGVVSAWDQV
SYFLFVIFTAYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL
FLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGLKMRPSLLMTR
YLESWGAAKPFAHLSHGDSPVSTSTPLPEKTLASFSTQWSLDRSRTPRGLDDELDTGDAK
FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFI
IQMLVTNRPPALAITYSITFLLFLLILFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRP
GLRIALGTATILLVFAMAITSLFFFPTSSDCPFQAPNVSSMISNLSWELPGSLPLISVPY
SMHCCTLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSECLIVRLYLGPLDS
RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL
LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR
LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV
EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST
GVLGKIQVTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG
Interacting with G-proteins:
G-proteins
NoNameRegulationPubMed
1Ggamma-12_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
2Gbeta-2_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
3Ggamma-8_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
4Ggamma-2_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
5Ggamma-t2_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
6Ggamma-11_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
7Ggamma-13_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
8Galpha-s_Homo sapiens_1Stimulation15251227 | 15922020 | 14993377 | 11376933
9Galpha-s_Homo sapiens_2Stimulation15251227 | 15922020 | 14993377 | 11376933
10Gbeta-5_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
11Ggamma-3_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
12Gbeta-like_Homo sapiens_1Stimulation15251227 | 15922020 | 14993377 | 11376933
13Gbeta-4_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
14Gbeta-like_Homo sapiens_2Stimulation15251227 | 15922020 | 14993377 | 11376933
15Ggamma-7_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
16Ggamma-5_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
17Gbeta-3_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
18Gbeta-1_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
19Ggamma-10_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
20Ggamma-t1_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
21Ggamma-4_Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level