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Description Entry page for GPCR - 'FORMYL-PEPTIDE RECEPTORS_FPR1_Homo sapiens'
ClassCLASS A
FamilyFORMYL-PEPTIDE RECEPTORS
Sub-FamilyFPR1
Cross References:
References
UniProtP21462 | Q14939 | Q7Z6A4 | Q86U52 | Q9NS48
EMBLM37128 | M60626 | M60627 | L10820 | AY301273 | BT007429 | AC018755 | BC005315 | S49810
InterProIPR000276 | IPR015691 | IPR000826 | IPR017452
PRODOM
GENEID2357
MIM136537
PRINTSPR00526 | PR00237
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameFORMYL-PEPTIDE RECEPTORS_FPR1_Homo sapiens
DescriptionRecName: Full=fMet-Leu-Phe receptor; Short=fMLP receptor;AltName: Full=N-formyl peptide receptor; Short=FPR;AltName: Full=N-formylpeptide chemoattractant receptor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneFPR
FunctionHigh affinity receptor for N-formyl-methionyl peptides,s which are powerful neutrophils chemotactic factors
Fragment0
Sequence
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVALQAK
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-z_Homo sapiensGi/o9336017
2Galpha-o_Homo sapiensGi/o9336017
3Galpha-i3_Homo sapiensGi/o9336017
4Galpha-i2_Homo sapiensGi/o9336017
5Galpha-i1_Homo sapiensGi/o9336017
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level