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Description Entry page for GPCR - 'MELANOCORTIN RECEPTORS_MC4_Homo sapiens'
ClassCLASS A
FamilyMELANOCORTIN RECEPTORS
Sub-FamilyMC4
Cross References:
References
UniProtP32245 | B2RAC3 | Q16317 | Q3MIJ6
EMBLL08603 | S77415 | AY236539 | AK314130 | CH471096 | BC069172 | BC101802 | BC111992
InterProIPR000276 | IPR017452 | IPR000155 | IPR001908 | IPR001671
PRODOM
GENEID4160
MIM155541 | 601665
PRINTSPR00237 | PR00534 | PR00535 | PR01062
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameMELANOCORTIN RECEPTORS_MC4_Homo sapiens
DescriptionRecName: Full=Melanocortin receptor 4;AltName: Full=MC4-R
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneMC4
FunctionReceptor specific to the heptapeptide core common tos adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH
Fragment0
Sequence
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-s_Homo sapiens_1Gs8392067
2Galpha-s_Homo sapiens_2Gs8392067
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level