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Description Entry page for GPCR - 'MUSCARINIC ACETYLCHOLINE RECEPTORS_M5_Homo sapiens'
ClassCLASS A
FamilyMUSCARINIC ACETYLCHOLINE RECEPTORS
Sub-FamilyM5
Cross References:
References
UniProtP08912 | Q96RG7
EMBLM80333 | AF026263 | AB084282 | AF498919 | AF385591
InterProIPR000276 | IPR017452 | IPR000502 | IPR000995
PRODOM
GENEID1133
MIM118496
PRINTSPR00237 | PR00243 | PR00542
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameMUSCARINIC ACETYLCHOLINE RECEPTORS_M5_Homo sapiens
DescriptionRecName: Full=Muscarinic acetylcholine receptor M5
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneCHRM
FunctionThe muscarinic acetylcholine receptor mediates variouss cellular responses, including inhibition of adenylate cyclase,s breakdown of phosphoinositides and modulation of potassiums channels through the action of G proteins
Fragment0
Sequence
MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE
KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL
TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN
YLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNP
NPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-11_Homo sapiensGq/113037705
2Galpha-q_Homo sapiensGq/113037705
3Galpha-14_Homo sapiensGq/113037705
4Galpha-15_Homo sapiensGq/113037705
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level