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Description Entry page for GPCR - 'NEUROMEDIN U RECEPTORS_NMU2_Homo sapiens'
ClassCLASS A
FamilyNEUROMEDIN U RECEPTORS
Sub-FamilyNMU2
Cross References:
References
UniProtQ9GZQ4 | Q7LC54 | Q96AM5 | Q9NRA6
EMBLAB041228 | AF272363 | AF292402 | AF242874 | BC016938 | BC067776
InterProIPR000276 | IPR017452 | IPR005390 | IPR005392
PRODOM
GENEID56923
MIM605108
PRINTSPR00237 | PR01565 | PR01567
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameNEUROMEDIN U RECEPTORS_NMU2_Homo sapiens
DescriptionRecName: Full=Neuromedin-U receptor 2; Short=NMU-R2;AltName: Full=G-protein coupled receptor TGR-1;AltName: Full=G-protein coupled receptor FM-4
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneNMUR2 | NMU2R,TGR
FunctionReceptor for the neuromedin-U and neuromedin-Ss neuropeptides (By similarity)
Fragment0
Sequence
MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGV
IGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCY
FKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLP
NTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMA
LRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSES
LAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPA
QRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPTALSSEQMSRTNYQSFHFNKT
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i2_Homo sapiensGi/o10894543
2Galpha-z_Homo sapiensGi/o10894543
3Galpha-11_Homo sapiensGq/1110894543
4Galpha-o_Homo sapiensGi/o10894543
5Galpha-15_Homo sapiensGq/1110894543
6Galpha-14_Homo sapiensGq/1110894543
7Galpha-q_Homo sapiensGq/1110894543
8Galpha-i3_Homo sapiensGi/o10894543
9Galpha-i1_Homo sapiensGi/o10894543
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level