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Description Entry page for GPCR - 'ADRENERGIC RECEPTORS_B3_Homo sapiens'
ClassCLASS A
FamilyADRENERGIC RECEPTORS
Sub-FamilyB3
Cross References:
References
UniProtP13945 | Q4JFT4
EMBLM29932 | X72861 | X70811 | X70812 | X70812 | AY487247 | DQ104441 | BC075017 | S53291
InterProIPR000276 | IPR000681 | IPR002233 | IPR017452
PRODOM
GENEID155
MIM109691
PRINTSPR01103 | PR00563 | PR00237
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameADRENERGIC RECEPTORS_B3_Homo sapiens
DescriptionRecName: Full=Beta-3 adrenergic receptor;AltName: Full=Beta-3 adrenoreceptor; Short=Beta-3 adrenoceptor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneADRB3 | ADRB3R,B3A
FunctionBeta-adrenergic receptors mediate the catecholamine-s induced activation of adenylate cyclase through the action of Gs proteins
Fragment0
Sequence
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-z_Homo sapiensGi/o9363896
2Galpha-s_Homo sapiens_1Gs2570461
3Galpha-s_Homo sapiens_2Gs2570461
4Galpha-i2_Homo sapiensGi/o9363896
5Galpha-i3_Homo sapiensGi/o9363896
6Galpha-i1_Homo sapiensGi/o9363896
7Galpha-o_Homo sapiensGi/o9363896
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level