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Description Entry page for G-protein - 'Ggamma-10_Homo sapiens'
ClassGgamma
FamilyGgamma
Sub-FamilyGgamma
TypeGgamma-10
Cross References:
References
UniProtP50151 | Q3B7K2 | Q4VC27
EMBLU31383 | AF493877 | AL135787 | BC010384 | BC015206 | BC016319 | BC072671 | BC107574
InterProIPR015898 | IPR001770
PRODOMPD003783
GENEID2790
MIM604389
PRINTSPR00321
PFAMPF00631
Details:
Details
NameGgamma-10_Homo sapiens
DescriptionRecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGNG10 | GNGT1
FunctionGuanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Fragment0
Sequence
MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR
EPRSCALL
Effectors:
Effectors
NoNameRegulationPubMed
1Voltage dependent P/Q type calcium channel-Homo sapiensInhibition15251227 | 11031246
2ATP-sensitive inward rectifier potassium channel 1-Homo sapiensStimulation15251227 | 10990455
3Calmodulin-Homo sapiensInhibition of calmodulin kinase15251227
4PI3K beta-Homo sapiensActivation9305878 | 12502714
5ATP-sensitive inward rectifier potassium channel 11-Homo sapiensStimulation15251227 | 10990455
6Dynamin 1-Homo sapiensIncreased GTPase activity15251227 | 14671004
7Tubulin-Homo sapiens-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
8Tubulin-Homo sapiens-26Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
9Phospholipase C beta 3-Homo sapiensStimulation15251227 | 11015615 | 8383116
10ATP-sensitive inward rectifier potassium channel 12-Homo sapiensStimulation15251227 | 10990455
11Tubulin-Homo sapiens-21Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
12SHC transforming protein 1-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
13Tubulin-Homo sapiens-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
14Tubulin-Homo sapiens-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
15Tubulin-Homo sapiens-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
16Cdc42-Homo sapiens"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
17Tubulin-Homo sapiens-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18Tubulin-Homo sapiens-22Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
19ATP-sensitive inward rectifier potassium channel 8-Homo sapiensStimulation15251227 | 10990455
20Adenylate cyclase 4-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
21Rho-Homo sapiens-2Recruitment to plasma membrane15251227
22Rac-Homo sapiens-3"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
23Tubulin-Homo sapiens-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
24Tubulin-Homo sapiens-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
25ATP-sensitive inward rectifier potassium channel 15-Homo sapiensStimulation15251227 | 10990455
26Ras specific nucleotide exchange factor CDC25-Homo sapiensStimulation (indirect activation of ras)15251227 | 8717044
27Tubulin-Homo sapiens-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
28Adenylate cyclase 5-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
29Tubulin-Homo sapiens-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
30Tubulin-Homo sapiens-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
31Voltage dependent R type calcium channel-Homo sapiensInhibition15251227 | 11031246
32Rho-Homo sapiens-1Recruitment to plasma membrane15251227
33Rac-Homo sapiens-2"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
34Tubulin-Homo sapiens-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
35Tubulin-Homo sapiens-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
36ATP-sensitive inward rectifier potassium channel 10-Homo sapiensStimulation15251227 | 10990455
37Kinase suppressor of Ras(KSR)-Homo sapiensSequestration of Gbeta/gamma15251227
38Tubulin-Homo sapiens-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
39Tubulin-Homo sapiens-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
40Tubulin-Homo sapiens-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
41Tubulin-Homo sapiens-27Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
42Tubulin-Homo sapiens-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
43Adenylate cyclase 6-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
44Rac-Homo sapiens-1"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
45Voltage dependent N type calcium channel-Homo sapiensInhibition15251227 | 11031246
46Adenylate cyclase 7-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
47Tubulin-Homo sapiens-25Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
48Tubulin-Homo sapiens-20Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
49SHC transforming protein 2-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
50Tubulin-Homo sapiens-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
51Adenylate cyclase 1-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933 | 10449730
52Tubulin-Homo sapiens-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
53Tubulin-Homo sapiens-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
54Phospholipase C beta 1-Homo sapiensStimulation15251227 | 11015615 | 8383116
55Rho-Homo sapiens-3Recruitment to plasma membrane15251227
56GRK3-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
57PI3K alpha-Homo sapiensPropable Inhibition16182515
58Tubulin-Homo sapiens-23Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
59ATP-sensitive inward rectifier potassium channel 14-Homo sapiensStimulation15251227 | 10990455
60Protein kinase D-Homo sapiensStimulation15251227
61PI3K gamma-Homo sapiensActivation12502714
62Brutons tyrosine kinase-Homo sapiensStimulation15251227 | 11698416
63Phospholipase C beta 2-Homo sapiensStimulation15251227 | 11015615 | 8383116
64GRK2-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
65Raf1 protein kinase-Homo sapiensSequestration of Gту15251227
66SHC transforming protein 3-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
67Adenylate cyclase 2-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
68Tsk tyrosine kinase-Homo sapiensStimulation15251227 | 14671004
69Tubulin-Homo sapiens-24Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
Interacton with GPCRs:
Coupling with GPCRs
NoNameCouplingPubMed