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Description Entry page for G-protein - 'Ggamma-11_Homo sapiens'
ClassGgamma
FamilyGgamma
Sub-FamilyGgamma
TypeGgamma-11
Cross References:
References
UniProtP61952 | P50152
EMBLU31384 | AF493878 | AC002076 | BC009709
InterProIPR015898 | IPR001770
PRODOMPD003783
GENEID2791
MIM604390
PRINTSPR00321
PFAMPF00631
Details:
Details
NameGgamma-11_Homo sapiens
DescriptionRecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGNG11 | GNGT1
FunctionGuanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Fragment0
Sequence
MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED
KNPFKEKGSCVIS
Effectors:
Effectors
NoNameRegulationPubMed
1Adenylate cyclase 2-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
2Tubulin-Homo sapiens-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
3Rho-Homo sapiens-1Recruitment to plasma membrane15251227
4ATP-sensitive inward rectifier potassium channel 14-Homo sapiensStimulation15251227 | 10990455
5Tubulin-Homo sapiens-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
6Adenylate cyclase 4-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
7Brutons tyrosine kinase-Homo sapiensStimulation15251227 | 11698416
8Phospholipase C beta 2-Homo sapiensStimulation15251227 | 11015615 | 8383116
9Adenylate cyclase 6-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
10ATP-sensitive inward rectifier potassium channel 8-Homo sapiensStimulation15251227 | 10990455
11Tubulin-Homo sapiens-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
12Adenylate cyclase 5-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
13Ras specific nucleotide exchange factor CDC25-Homo sapiensStimulation (indirect activation of ras)15251227 | 8717044
14Raf1 protein kinase-Homo sapiensSequestration of G15251227
15Tubulin-Homo sapiens-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
16Dynamin 1-Homo sapiensIncreased GTPase activity15251227 | 14671004
17Adenylate cyclase 7-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
18Tubulin-Homo sapiens-24Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
19Tubulin-Homo sapiens-25Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
20Rho-Homo sapiens-3Recruitment to plasma membrane15251227
21Tubulin-Homo sapiens-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
22GRK2-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
23Tubulin-Homo sapiens-20Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
24Phospholipase C beta 1-Homo sapiensStimulation15251227 | 11015615 | 8383116
25Tubulin-Homo sapiens-27Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
26Tubulin-Homo sapiens-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
27Tubulin-Homo sapiens-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
28Adenylate cyclase 1-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933 | 10449730
29Tubulin-Homo sapiens-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
30Tubulin-Homo sapiens-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
31ATP-sensitive inward rectifier potassium channel 11-Homo sapiensStimulation15251227 | 10990455
32ATP-sensitive inward rectifier potassium channel 1-Homo sapiensStimulation15251227 | 10990455
33Rac-Homo sapiens-1"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
34SHC transforming protein 3-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
35Tubulin-Homo sapiens-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
36PI3K alpha-Homo sapiensPropable Inhibition16182515
37SHC transforming protein 1-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
38ATP-sensitive inward rectifier potassium channel 15-Homo sapiensStimulation15251227 | 10990455
39Tubulin-Homo sapiens-21Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
40Tubulin-Homo sapiens-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
41Rac-Homo sapiens-2"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
42Rho-Homo sapiens-2Recruitment to plasma membrane15251227
43Tsk tyrosine kinase-Homo sapiensStimulation15251227 | 14671004
44Voltage dependent P/Q type calcium channel-Homo sapiensInhibition15251227 | 11031246
45Tubulin-Homo sapiens-26Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
46SHC transforming protein 2-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
47GRK3-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
48Cdc42-Homo sapiens"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
49Tubulin-Homo sapiens-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
50Voltage dependent N type calcium channel-Homo sapiensInhibition15251227 | 11031246
51Tubulin-Homo sapiens-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
52Rac-Homo sapiens-3"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
53Tubulin-Homo sapiens-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
54Tubulin-Homo sapiens-23Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
55Voltage dependent R type calcium channel-Homo sapiensInhibition15251227 | 11031246
56ATP-sensitive inward rectifier potassium channel 10-Homo sapiensStimulation15251227 | 10990455
57Tubulin-Homo sapiens-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
58Calmodulin-Homo sapiensInhibition of calmodulin kinase15251227
59Tubulin-Homo sapiens-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
60Protein kinase D-Homo sapiensStimulation15251227
61ATP-sensitive inward rectifier potassium channel 12-Homo sapiensStimulation15251227 | 10990455
62Tubulin-Homo sapiens-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
63Tubulin-Homo sapiens-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
64Phospholipase C beta 3-Homo sapiensStimulation15251227 | 11015615 | 8383116
65Kinase suppressor of Ras(KSR)-Homo sapiensSequestration of Gbeta/gamma15251227
66PI3K gamma-Homo sapiensActivation12502714
67PI3K beta-Homo sapiensActivation9305878 | 12502714
68Tubulin-Homo sapiens-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
69Tubulin-Homo sapiens-22Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
Interacton with GPCRs:
Coupling with GPCRs
NoNameCouplingPubMed