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Description Entry page for G-protein - 'Ggamma-13_Homo sapiens'
ClassGgamma
FamilyGgamma
Sub-FamilyGgamma
TypeGgamma-13
Cross References:
References
UniProtQ9P2W3 | B2R5C8 | Q52LX0 | Q9UJJ3
EMBLAY029486 | AB030207 | AF493880 | AK312139 | AE006465 | AL031033 | BC093760 | BC095525
InterProIPR015898 | IPR001770
PRODOMPD003783
GENEID51764
MIM607298
PRINTSPR00321
PFAMPF00631
Details:
Details
NameGgamma-13_Homo sapiens
DescriptionRecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGNG1
FunctionGuanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Fragment0
Sequence
MEEWDVPQMKKEVESLKYQLAFQREMASKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVE
KGKCTIL
Effectors:
Effectors
NoNameRegulationPubMed
1Tubulin-Homo sapiens-22Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
2Tubulin-Homo sapiens-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
3ATP-sensitive inward rectifier potassium channel 10-Homo sapiensStimulation15251227 | 10990455
4Tubulin-Homo sapiens-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
5Rho-Homo sapiens-3Recruitment to plasma membrane15251227
6SHC transforming protein 3-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
7Phospholipase C beta 3-Homo sapiensStimulation15251227 | 11015615 | 8383116
8ATP-sensitive inward rectifier potassium channel 14-Homo sapiensStimulation15251227 | 10990455
9PI3K beta-Homo sapiensActivation9305878 | 12502714
10Rho-Homo sapiens-1Recruitment to plasma membrane15251227
11Voltage dependent R type calcium channel-Homo sapiensInhibition15251227 | 11031246
12Tubulin-Homo sapiens-20Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
13Tubulin-Homo sapiens-27Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
14Tubulin-Homo sapiens-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
15Adenylate cyclase 6-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
16Tubulin-Homo sapiens-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
17Tubulin-Homo sapiens-26Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18Tubulin-Homo sapiens-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
19Protein kinase D-Homo sapiensStimulation15251227
20Tubulin-Homo sapiens-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
21ATP-sensitive inward rectifier potassium channel 8-Homo sapiensStimulation15251227 | 10990455
22Adenylate cyclase 2-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
23ATP-sensitive inward rectifier potassium channel 12-Homo sapiensStimulation15251227 | 10990455
24Rho-Homo sapiens-2Recruitment to plasma membrane15251227
25Adenylate cyclase 4-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
26Ras specific nucleotide exchange factor CDC25-Homo sapiensStimulation (indirect activation of ras)15251227 | 8717044
27Tubulin-Homo sapiens-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
28Tubulin-Homo sapiens-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
29Rac-Homo sapiens-3"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
30Tubulin-Homo sapiens-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
31Brutons tyrosine kinase-Homo sapiensStimulation15251227 | 11698416
32GRK2-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
33Tubulin-Homo sapiens-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
34Cdc42-Homo sapiens"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
35Adenylate cyclase 7-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
36Phospholipase C beta 2-Homo sapiensStimulation15251227 | 11015615 | 8383116
37Tsk tyrosine kinase-Homo sapiensStimulation15251227 | 14671004
38Tubulin-Homo sapiens-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
39Kinase suppressor of Ras(KSR)-Homo sapiensSequestration of Gbeta/gamma15251227
40Tubulin-Homo sapiens-21Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
41Phospholipase C beta 1-Homo sapiensStimulation15251227 | 11015615 | 8383116
42GRK3-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
43Tubulin-Homo sapiens-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
44Dynamin 1-Homo sapiensIncreased GTPase activity15251227 | 14671004
45Tubulin-Homo sapiens-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
46Adenylate cyclase 1-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933 | 10449730
47Rac-Homo sapiens-2"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
48ATP-sensitive inward rectifier potassium channel 1-Homo sapiensStimulation15251227 | 10990455
49PI3K alpha-Homo sapiensPropable Inhibition16182515
50Tubulin-Homo sapiens-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
51Tubulin-Homo sapiens-25Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
52Tubulin-Homo sapiens-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
53Tubulin-Homo sapiens-24Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
54Calmodulin-Homo sapiensInhibition of calmodulin kinase15251227
55SHC transforming protein 1-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
56ATP-sensitive inward rectifier potassium channel 15-Homo sapiensStimulation15251227 | 10990455
57Tubulin-Homo sapiens-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
58Voltage dependent N type calcium channel-Homo sapiensInhibition15251227 | 11031246
59SHC transforming protein 2-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
60Tubulin-Homo sapiens-23Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
61Voltage dependent P/Q type calcium channel-Homo sapiensInhibition15251227 | 11031246
62Adenylate cyclase 5-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
63PI3K gamma-Homo sapiensActivation12502714
64ATP-sensitive inward rectifier potassium channel 11-Homo sapiensStimulation15251227 | 10990455
65Raf1 protein kinase-Homo sapiensSequestration of G15251227
66Rac-Homo sapiens-1"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
67Tubulin-Homo sapiens-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
68Tubulin-Homo sapiens-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
69Tubulin-Homo sapiens-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
Interacton with GPCRs:
Coupling with GPCRs
NoNameCouplingPubMed