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Description Entry page for G-protein - 'Ggamma-t1_Homo sapiens'
ClassGgamma
FamilyGgamma
Sub-FamilyGgamma
TypeGgamma-t1
Cross References:
References
UniProtP63211 | O43835 | Q08447 | Q16026
EMBLS62027 | S62026 | AF493869 | CR456912 | AC002076 | BC029367 | U41492
InterProIPR015898 | IPR001770
PRODOMPD003783
GENEID2792
MIM189970
PRINTSPR00321
PFAMPF00631
Details:
Details
NameGgamma-t1_Homo sapiens
DescriptionRecName: Full=Guanine nucleotide-binding protein G(T) subunit gamma-T1;AltName: Full=Transducin gamma chain;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGNGT
FunctionGuanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Fragment0
Sequence
MPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPED
KNPFKELKGGCVIS
Effectors:
Effectors
NoNameRegulationPubMed
1GRK3-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
2Tubulin-Homo sapiens-23Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
3Tubulin-Homo sapiens-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
4Tubulin-Homo sapiens-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
5Cdc42-Homo sapiens"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
6Adenylate cyclase 7-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
7Voltage dependent P/Q type calcium channel-Homo sapiensInhibition15251227 | 11031246
8Voltage dependent N type calcium channel-Homo sapiensInhibition15251227 | 11031246
9Tubulin-Homo sapiens-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
10Tubulin-Homo sapiens-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
11Rac-Homo sapiens-2"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
12Phospholipase C beta 2-Homo sapiensStimulation15251227 | 11015615 | 8383116
13Adenylate cyclase 1-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933 | 10449730
14Tubulin-Homo sapiens-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
15Phospholipase C beta 3-Homo sapiensStimulation15251227 | 11015615 | 8383116
16Tubulin-Homo sapiens-20Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
17Tubulin-Homo sapiens-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18Kinase suppressor of Ras(KSR)-Homo sapiensSequestration of Gbeta/gamma15251227
19Rho-Homo sapiens-1Recruitment to plasma membrane15251227
20PI3K alpha-Homo sapiensPropable Inhibition16182515
21Dynamin 1-Homo sapiensIncreased GTPase activity15251227 | 14671004
22Rac-Homo sapiens-3"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
23Rho-Homo sapiens-3Recruitment to plasma membrane15251227
24Phospholipase C beta 1-Homo sapiensStimulation15251227 | 11015615 | 8383116
25PI3K gamma-Homo sapiensActivation12502714
26Tubulin-Homo sapiens-27Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
27Tubulin-Homo sapiens-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
28ATP-sensitive inward rectifier potassium channel 15-Homo sapiensStimulation15251227 | 10990455
29Tsk tyrosine kinase-Homo sapiensStimulation15251227 | 14671004
30GRK2-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
31Tubulin-Homo sapiens-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
32ATP-sensitive inward rectifier potassium channel 10-Homo sapiensStimulation15251227 | 10990455
33ATP-sensitive inward rectifier potassium channel 11-Homo sapiensStimulation15251227 | 10990455
34Tubulin-Homo sapiens-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
35Tubulin-Homo sapiens-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
36Brutons tyrosine kinase-Homo sapiensStimulation15251227 | 11698416
37Tubulin-Homo sapiens-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
38SHC transforming protein 1-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
39Tubulin-Homo sapiens-22Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
40Ras specific nucleotide exchange factor CDC25-Homo sapiensStimulation (indirect activation of ras)15251227 | 8717044
41Tubulin-Homo sapiens-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
42ATP-sensitive inward rectifier potassium channel 1-Homo sapiensStimulation15251227 | 10990455
43Tubulin-Homo sapiens-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
44Tubulin-Homo sapiens-26Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
45Adenylate cyclase 2-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
46Adenylate cyclase 5-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
47Rho-Homo sapiens-2Recruitment to plasma membrane15251227
48Protein kinase D-Homo sapiensStimulation15251227
49Raf1 protein kinase-Homo sapiensSequestration of G15251227
50Tubulin-Homo sapiens-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
51Calmodulin-Homo sapiensInhibition of calmodulin kinase15251227
52Tubulin-Homo sapiens-25Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
53Tubulin-Homo sapiens-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
54Voltage dependent R type calcium channel-Homo sapiensInhibition15251227 | 11031246
55Tubulin-Homo sapiens-21Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
56Tubulin-Homo sapiens-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
57Rac-Homo sapiens-1"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
58ATP-sensitive inward rectifier potassium channel 8-Homo sapiensStimulation15251227 | 10990455
59PI3K beta-Homo sapiensActivation9305878 | 12502714
60Tubulin-Homo sapiens-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
61SHC transforming protein 3-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
62Adenylate cyclase 6-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
63ATP-sensitive inward rectifier potassium channel 12-Homo sapiensStimulation15251227 | 10990455
64Tubulin-Homo sapiens-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
65Adenylate cyclase 4-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
66ATP-sensitive inward rectifier potassium channel 14-Homo sapiensStimulation15251227 | 10990455
67SHC transforming protein 2-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
68Tubulin-Homo sapiens-24Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
69Tubulin-Homo sapiens-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
Interacton with GPCRs:
Coupling with GPCRs
NoNameCouplingPubMed