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Description Entry page for G-protein - 'Ggamma-3_Homo sapiens'
ClassGgamma
FamilyGgamma
Sub-FamilyGgamma
TypeGgamma-3
Cross References:
References
UniProtP63215 | B2R4S7 | P29798 | Q61014
EMBLAF092129 | AF188177 | AF087900 | AF493871 | AK311933 | CH471076 | BC015563
InterProIPR015898 | IPR001770
PRODOMPD003783
GENEID2785
MIM608941
PRINTSPR00321
PFAMPF00631
Details:
Details
NameGgamma-3_Homo sapiens
DescriptionRecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGNG3 | GNGT
FunctionGuanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Fragment0
Sequence
MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT
SENPFREKKFFCALL
Effectors:
Effectors
NoNameRegulationPubMed
1Adenylate cyclase 4-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
2Tubulin-Homo sapiens-23Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
3PI3K gamma-Homo sapiensActivation12502714
4Phospholipase C beta 1-Homo sapiensStimulation15251227 | 11015615 | 8383116
5Brutons tyrosine kinase-Homo sapiensStimulation15251227 | 11698416
6Adenylate cyclase 2-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
7Tubulin-Homo sapiens-25Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
8Tubulin-Homo sapiens-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
9Tubulin-Homo sapiens-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
10SHC transforming protein 2-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
11ATP-sensitive inward rectifier potassium channel 10-Homo sapiensStimulation15251227 | 10990455
12GRK2-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
13ATP-sensitive inward rectifier potassium channel 1-Homo sapiensStimulation15251227 | 10990455
14Tubulin-Homo sapiens-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
15Tubulin-Homo sapiens-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
16Tsk tyrosine kinase-Homo sapiensStimulation15251227 | 14671004
17Tubulin-Homo sapiens-20Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18ATP-sensitive inward rectifier potassium channel 8-Homo sapiensStimulation15251227 | 10990455
19ATP-sensitive inward rectifier potassium channel 12-Homo sapiensStimulation15251227 | 10990455
20Cdc42-Homo sapiens"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
21Tubulin-Homo sapiens-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
22Tubulin-Homo sapiens-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
23Raf1 protein kinase-Homo sapiensSequestration of G15251227
24Tubulin-Homo sapiens-26Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
25Tubulin-Homo sapiens-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
26Tubulin-Homo sapiens-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
27Tubulin-Homo sapiens-27Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
28ATP-sensitive inward rectifier potassium channel 14-Homo sapiensStimulation15251227 | 10990455
29Rho-Homo sapiens-3Recruitment to plasma membrane15251227
30PI3K alpha-Homo sapiensPropable Inhibition16182515
31Tubulin-Homo sapiens-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
32Tubulin-Homo sapiens-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
33Tubulin-Homo sapiens-24Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
34Tubulin-Homo sapiens-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
35Adenylate cyclase 6-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
36Protein kinase D-Homo sapiensStimulation15251227
37Dynamin 1-Homo sapiensIncreased GTPase activity15251227 | 14671004
38Rho-Homo sapiens-1Recruitment to plasma membrane15251227
39Rac-Homo sapiens-3"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
40ATP-sensitive inward rectifier potassium channel 15-Homo sapiensStimulation15251227 | 10990455
41Tubulin-Homo sapiens-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
42Tubulin-Homo sapiens-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
43Tubulin-Homo sapiens-21Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
44Tubulin-Homo sapiens-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
45SHC transforming protein 3-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
46Adenylate cyclase 1-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933 | 10449730
47PI3K beta-Homo sapiensActivation9305878 | 12502714
48Tubulin-Homo sapiens-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
49Phospholipase C beta 3-Homo sapiensStimulation15251227 | 11015615 | 8383116
50Adenylate cyclase 7-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
51Tubulin-Homo sapiens-22Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
52GRK3-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
53ATP-sensitive inward rectifier potassium channel 11-Homo sapiensStimulation15251227 | 10990455
54Voltage dependent R type calcium channel-Homo sapiensInhibition15251227 | 11031246
55Tubulin-Homo sapiens-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
56Tubulin-Homo sapiens-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
57Rac-Homo sapiens-2"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
58Calmodulin-Homo sapiensInhibition of calmodulin kinase15251227
59Adenylate cyclase 5-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
60Kinase suppressor of Ras(KSR)-Homo sapiensSequestration of Gbeta/gamma15251227
61Phospholipase C beta 2-Homo sapiensStimulation15251227 | 11015615 | 8383116
62SHC transforming protein 1-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
63Rac-Homo sapiens-1"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
64Voltage dependent N type calcium channel-Homo sapiensInhibition15251227 | 11031246
65Ras specific nucleotide exchange factor CDC25-Homo sapiensStimulation (indirect activation of ras)15251227 | 8717044
66Tubulin-Homo sapiens-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
67Tubulin-Homo sapiens-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
68Voltage dependent P/Q type calcium channel-Homo sapiensInhibition15251227 | 11031246
69Rho-Homo sapiens-2Recruitment to plasma membrane15251227
Interacton with GPCRs:
Coupling with GPCRs
NoNameCouplingPubMed