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Description Entry page for G-protein - 'Ggamma-5_Homo sapiens'
ClassGgamma
FamilyGgamma
Sub-FamilyGgamma
TypeGgamma-5
Cross References:
References
UniProtP63218 | B2R5A0 | P30670 | Q5VX54 | Q61015
EMBLAF085709 | AF085708 | AF038955 | AF493873 | BT006823 | AK312111 | AL359762 | CH471097 | BC003563
InterProIPR015898 | IPR001770
PRODOMPD003783
GENEID2787
MIM600874
PRINTSPR00321
PFAMPF00631
Details:
Details
NameGgamma-5_Homo sapiens
DescriptionRecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGNG5 | GNGT
FunctionGuanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Fragment0
Sequence
MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFR
PQKVCSFL
Effectors:
Effectors
NoNameRegulationPubMed
1Tubulin-Homo sapiens-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
2GRK3-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
3Tubulin-Homo sapiens-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
4Rac-Homo sapiens-2"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
5Calmodulin-Homo sapiensInhibition of calmodulin kinase15251227
6Tubulin-Homo sapiens-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
7Tubulin-Homo sapiens-27Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
8Brutons tyrosine kinase-Homo sapiensStimulation15251227 | 11698416
9ATP-sensitive inward rectifier potassium channel 15-Homo sapiensStimulation15251227 | 10990455
10Tubulin-Homo sapiens-20Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
11Protein kinase D-Homo sapiensStimulation15251227
12Adenylate cyclase 6-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
13Tubulin-Homo sapiens-26Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
14Ras specific nucleotide exchange factor CDC25-Homo sapiensStimulation (indirect activation of ras)15251227 | 8717044
15Tubulin-Homo sapiens-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
16Tubulin-Homo sapiens-24Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
17Tubulin-Homo sapiens-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18PI3K beta-Homo sapiensActivation9305878 | 12502714
19Tubulin-Homo sapiens-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
20Tsk tyrosine kinase-Homo sapiensStimulation15251227 | 14671004
21Rac-Homo sapiens-3"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
22Tubulin-Homo sapiens-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
23Tubulin-Homo sapiens-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
24Adenylate cyclase 1-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933 | 10449730
25Tubulin-Homo sapiens-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
26Tubulin-Homo sapiens-25Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
27Rho-Homo sapiens-1Recruitment to plasma membrane15251227
28GRK2-Homo sapiensRecruitment to plasma membrane15251227 | 14654303
29Raf1 protein kinase-Homo sapiensSequestration of G15251227
30Adenylate cyclase 5-Homo sapiensInhibition15251227 | 15922020 | 14993377 | 11376933
31Tubulin-Homo sapiens-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
32Phospholipase C beta 3-Homo sapiensStimulation15251227 | 11015615 | 8383116
33Adenylate cyclase 7-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
34Tubulin-Homo sapiens-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
35SHC transforming protein 1-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
36Tubulin-Homo sapiens-22Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
37Tubulin-Homo sapiens-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
38ATP-sensitive inward rectifier potassium channel 14-Homo sapiensStimulation15251227 | 10990455
39Tubulin-Homo sapiens-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
40ATP-sensitive inward rectifier potassium channel 11-Homo sapiensStimulation15251227 | 10990455
41ATP-sensitive inward rectifier potassium channel 12-Homo sapiensStimulation15251227 | 10990455
42ATP-sensitive inward rectifier potassium channel 8-Homo sapiensStimulation15251227 | 10990455
43Tubulin-Homo sapiens-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
44PI3K alpha-Homo sapiensPropable Inhibition16182515
45ATP-sensitive inward rectifier potassium channel 10-Homo sapiensStimulation15251227 | 10990455
46Rac-Homo sapiens-1"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
47Tubulin-Homo sapiens-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
48SHC transforming protein 2-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
49Voltage dependent N type calcium channel-Homo sapiensInhibition15251227 | 11031246
50Tubulin-Homo sapiens-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
51Adenylate cyclase 4-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
52ATP-sensitive inward rectifier potassium channel 1-Homo sapiensStimulation15251227 | 10990455
53Rho-Homo sapiens-2Recruitment to plasma membrane15251227
54Voltage dependent P/Q type calcium channel-Homo sapiensInhibition15251227 | 11031246
55Voltage dependent R type calcium channel-Homo sapiensInhibition15251227 | 11031246
56Cdc42-Homo sapiens"Stimulation,Recruitment to plasma membrane"11099498 | 15251227
57Tubulin-Homo sapiens-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
58Phospholipase C beta 2-Homo sapiensStimulation15251227 | 11015615 | 8383116
59Rho-Homo sapiens-3Recruitment to plasma membrane15251227
60Phospholipase C beta 1-Homo sapiensStimulation15251227 | 11015615 | 8383116
61Tubulin-Homo sapiens-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
62PI3K gamma-Homo sapiensActivation12502714
63Kinase suppressor of Ras(KSR)-Homo sapiensSequestration of Gbeta/gamma15251227
64Adenylate cyclase 2-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
65Tubulin-Homo sapiens-21Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
66SHC transforming protein 3-Homo sapiensStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
67Tubulin-Homo sapiens-23Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
68Dynamin 1-Homo sapiensIncreased GTPase activity15251227 | 14671004
69Tubulin-Homo sapiens-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
Interacton with GPCRs:
Coupling with GPCRs
NoNameCouplingPubMed