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Summary sheet information for Effector 'Src tyrosine kinase-Homo sapiens-1'
Name Src tyrosine kinase-Homo sapiens-1
Description RecName: Full=Tyrosine-protein kinase CSK; EC=2.7.10.2;AltName: Full=C-SRC kinase;AltName: Full=Protein-tyrosine kinase CYL
Class
Family Tyr protein kinases
Sub_family Tyr protein kinases
type Src tyrosine kinase
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 15
Gene Start: 72861768
Gene End: 72882557
Ensembl Contig View

Ensembl Genes:
ENSG00000103653

EMBL:
EMBL ID  Description
AK223626  Homo sapiens mRNA for c-src tyrosine kinase variant, clone: FCC134G03.
AK290531  Homo sapiens cDNA FLJ78579 complete cds, highly similar to Homo sapiens c-src tyrosine kinase (CSK), mRNA.
AK312669  Homo sapiens cDNA, FLJ93062, Homo sapiens c-src tyrosine kinase (CSK), mRNA.
BC104847  Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:132507 IMAGE:8143850), complete cds.
BC104875  Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:132535 IMAGE:8143878), complete cds.
BC106073  Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:117393 IMAGE:6526810), complete cds.
CH471136  Homo sapiens 211000035841687 genomic scaffold, whole genome shotgun sequence.
CR541960  Homo sapiens full open reading frame cDNA clone RZPDo834E0634D for gene CSK, c-src tyrosine kinase; complete cds, without stopcodon.
DQ075211  Homo sapiens c-src tyrosine kinase (CSK) gene, complete cds.
X59932  Human mRNA for C-SRC-kinase
X60114  H.sapiens cyl mRNA for cytoplasmic tryrosine kinase
X74765  Homo sapiens CSK gene for protein tyrosine kinase

EntrezGene:
ID  Description
CSK  c-src tyrosine kinase

RefSeq DNA:
ID  Description
NM_001127190  Homo sapiens c-src tyrosine kinase (CSK), transcript variant 2, mRNA.
NM_004383  Homo sapiens c-src tyrosine kinase (CSK), transcript variant 1, mRNA.

UniGene:
ID  Description
Hs.77793  CSK mRNA for c-src tyrosine kinase, complete cds, clone: FLJ08127AAAN

Proteins
Ensembl Proteins:
ENSP00000220003

Entrez Proteins:
AAI04848.1; AAI04876.1; AAI06074.1; AAY57329.1; BAD97346.1; BAF83220.1; BAG35551.1; CAA42556.1; CAA42713.1; CAB58562.1; CAG46758.1; EAW99311.1

RefSeq Proteins:
ID  Description
NP_001120662  c-src tyrosine kinase [Homo sapiens].
NP_004374  c-src tyrosine kinase [Homo sapiens].

UniProt:
ID  Description
A8K3B6  SubName: Full=cDNA FLJ78579, highly similar to Homo sapiens c-src tyrosine kinase (CSK), mRNA;
B2R6Q4  SubName: Full=cDNA FLJ45770 fis, clone NETRP2002197, highly similar to Tyrosine-protein kinase CSK (EC 2.7.10.2); SubName: Full=C-src tyrosine kinase, isoform CRA_a; SubName: Full=cDNA, FLJ93062, Homo sapiens c-src tyrosine kinase (CSK), mRNA;
Q53EL3  SubName: Full=C-src tyrosine kinase variant; Flags: Fragment;
P41240  RecName: Full=Tyrosine-protein kinase CSK; EC=2.7.10.2; AltName: Full=C-SRC kinase; AltName: Full=Protein-tyrosine kinase CYL;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Src tyrosine kinase-Homo sapiens-1    

InterPro:
ID  Name
IPR001452  SH3_domain
IPR000719  Prot_kinase_core
IPR001245  Tyr_pkinase
IPR015778  Tyrosine_Protein_Kinase_Csk
IPR017441  Protein_kinase_ATP_bd_CS
IPR008266  Tyr_pkinase_AS
IPR000980  SH2

Pfam:
ID  Description
SH2  SH2 domain
SH3_1  SH3 domain
Pkinase_Tyr  Protein tyrosine kinase

Structure
PDB:
ID
1BYG
1CSK
3D7T
3D7U

HSSP:
ID  Description
1a07  COMPLEX (TRANSFERASE/PEPTIDE)
1a08  COMPLEX (TRANSFERASE/PEPTIDE)
1a09  COMPLEX (TRANSFERASE/PEPTIDE)
1a1a  COMPLEX (TRANSFERASE/PEPTIDE)
1a1b  COMPLEX (TRANSFERASE/PEPTIDE)
1a1c  COMPLEX (TRANSFERASE/PEPTIDE)
1a1e  COMPLEX (TRANSFERASE/PEPTIDE)
1a81  COMPLEX (TRANSFERASE/PEPTIDE)
1ab2  TRANSFERASE(PHOSPHOTRANSFERASE)
1ad5  TYROSINE-PROTEIN KINASE
1agw  PROTEIN KINASE
1aot  COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN)
1aou  COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN)
1aww  TRANSFERASE
1awx  TRANSFERASE
1aya  HYDROLASE(SH2 DOMAIN)
1ayb  HYDROLASE(SH2 DOMAIN)
1ayc  HYDROLASE(SH2 DOMAIN)
1ayd  HYDROLASE(SH2 DOMAIN)
1aze  COMPLEX (ADAPTOR PROTEIN/PEPTIDE)
1b07  SH3 DOMAIN
1bfi  SH2 DOMAIN
1bfj  SH2 DOMAIN
1bhf  COMPLEX (SH2 DOMAIN/INHIBITOR)
1bhh  SH2 DOMAIN
1bkl  V-SRC SH2 DOMAIN
1bkm  TRANSFORMING PROTEIN
1blj  PHOSPHORYLATION
1blk  PHOSPHORYLATION
1bm2  HORMONE/GROWTH FACTOR
1bmb  HORMONE/GROWTH FACTOR
1bu1  TRANSFERASE
1byg  TRANSFERASE
1cj1  SIGNALING PROTEIN
1cka  COMPLEX (ONCOGENE PROTEIN/PEPTIDE)
1ckb  COMPLEX (ONCOGENE PROTEIN/PEPTIDE)
1csk  PHOSPHOTRANSFERASE
1csy  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1csz  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1cwd  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1cwe  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1d1z  GENE REGULATION
1d4t  SIGNALING PROTEIN
1d4w  SIGNALING PROTEIN
1f1w  TRANSFERASE
1f2f  TRANSFERASE
1fbz  TRANSFERASE
1fgi  PROTEIN KINASE
1fgk  PHOSPHOTRANSFERASE
1fmk  PHOSPHOTRANSFERASE
1fpu  TRANSFERASE
1fvr  TRANSFERASE
1fyr  HORMONE/GROWTH FACTOR
1g83  TRANSFERASE
1gag  TRANSFERASE, SIGNALING PROTEIN
1gbq  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1gbr  SIGNAL TRANSDUCTION PROTEIN
1ghu  SRC HOMOLOGY 2 DOMAIN
1gjo  TRANSFERASE
1gl5  TRANSFERASE
1h9o  COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR)
1hcs  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1hct  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1i3z  SIGNALING PROTEIN
1i44  TRANSFERASE
1iep  TRANSFERASE
1ijr  TRANSFERASE/SIGNALING PROTEIN
1ir3  COMPLEX (TRANSFERASE/SUBSTRATE)
1irk  TRANSFERASE (PHOSPHOTRANSFERASE)
1is0  TRANSFERASE
1jeg  TRANSFERASE/HYDROLASE
1jpa  TRANSFERASE
1jqh  TRANSFERASE
1ju5  PROTEIN BINDING/TRANSFERASE
1jwo  TRANSFERASE
1jyq  SIGNALING PROTEIN
1jyr  SIGNALING PROTEIN
1jyu  SIGNALING PROTEIN
1k2p  TRANSFERASE
1k3a  TRANSFERASE
1k9a  TRANSFERASE
1ka6  IMMUNE SYSTEM
1ka7  IMMUNE SYSTEM
1kc2  TRANSFERASE
1ksw  TRANSFERASE
1lcj  COMPLEX (KINASE/PEPTIDE)
1lck  COMPLEX (KINASE/PEPTIDE)
1lkk  COMPLEX (TYROSINE KINASE/PEPTIDE)
1lkl  COMPLEX (TYROSINE KINASE/PEPTIDE)
1luf  TRANSFERASE
1lui  TRANSFERASE
1luk  TRANSFERASE
1lum  TRANSFERASE
1lun  TRANSFERASE
1m14  TRANSFERASE
1m17  TRANSFERASE
1m27  SIGNALING PROTEIN, TRANSFERASE
1m30  PROTEIN BINDING
1m3a  PROTEIN BINDING
1m3b  PROTEIN BINDING
1m3c  PROTEIN BINDING
1m52  TRANSFERASE
1m61  TRANSFERASE
1m7n  TRANSFERASE
1mil  TRANSFORMING PROTEIN
1mp8  TRANSFERASE
1mqb  TRANSFERASE
1mw4  HORMONE/GROWTH FACTOR/TRANSFERASE
1nzl  TRANSFERASE
1nzv  TRANSFERASE
1o41  SIGNALING PROTEIN
1o42  SIGNALING PROTEIN
1o43  SIGNALING PROTEIN
1o44  SIGNALING PROTEIN
1o45  SIGNALING PROTEIN
1o46  SIGNALING PROTEIN
1o47  SIGNALING PROTEIN
1o48  SIGNALING PROTEIN
1o49  SIGNALING PROTEIN
1o4a  SIGNALING PROTEIN
1o4b  SIGNALING PROTEIN
1o4c  SIGNALING PROTEIN
1o4d  SIGNALING PROTEIN
1o4e  SIGNALING PROTEIN
1o4f  SIGNALING PROTEIN
1o4g  SIGNALING PROTEIN
1o4h  SIGNALING PROTEIN
1o4i  SIGNALING PROTEIN
1o4j  SIGNALING PROTEIN
1o4k  SIGNALING PROTEIN
1o4l  SIGNALING PROTEIN
1o4m  SIGNALING PROTEIN
1o4n  SIGNALING PROTEIN
1o4o  SIGNALING PROTEIN
1o4p  SIGNALING PROTEIN
1o4q  SIGNALING PROTEIN
1o4r  SIGNALING PROTEIN
1oec  TRANSFERASE
1oot  STRUCTURAL GENOMICS
1opj  TRANSFERASE
1opk  TRANSFERASE
1opl  TRANSFERASE
1p13  TRANSFERASE
1p14  TRANSFERASE
1p4o  HORMONE/GROWTH FACTOR
1pic  COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR)
1pkg  TRANSFERASE ACTIVATOR
1qad  TRANSFERASE
1qcf  TYROSINE KINASE
1qg1  HORMONE/GROWTH FACTOR
1qly  TYROSINE-PROTEIN KINASE
1qpc  TRANSFERASE
1qpd  TRANSFERASE
1qpe  TRANSFERASE
1qpj  TRANSFERASE
1r0p  TRANSFERASE
1r1w  TRANSFERASE
1rja  TRANSFERASE
1rjb  TRANSFERASE
1rpy  SIGNALING PROTEIN
1s1n  CELL ADHESION
1sha  PHOSPHOTRANSFERASE
1shb  PHOSPHOTRANSFERASE
1shd  COMPLEX(TRANSFERASE/PEPTIDE)
1skj  TYROSINE-PROTEIN KINASE
1sm2  TRANSFERASE
1snu  TRANSFERASE
1snx  TRANSFERASE
1spr  TRANSFERASE(PHOSPHOTRANSFERASE)
1sps  TRANSFERASE(PHOSPHOTRANSFERASE)
1ssh  CONTRACTILE PROTEIN
1t45  TRANSFERASE ACTIVATOR
1t46  TRANSFERASE ACTIVATOR
1tce  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1tze  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1u46  TRANSFERASE
1u4d  TRANSFERASE
1u54  TRANSFERASE
1u59  TRANSFERASE
1u5s  METAL BINDING PROTEIN
1ujy  SIGNALING PROTEIN
1uwj  KINASE
1vjy  TRANSFERASE
1vr2  TRANSFERASE
1w1f  SH3-DOMAIN
1wa7  SH3 DOMAIN
1wx6  STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1x0n  PEPTIDE BINDING PROTEIN
1x27  SIGNALING PROTEIN
1x2k  SIGNALING PROTEIN
1x2p  TRANSFERASE
1x6c  SIGNALING PROTEIN
1x6g  SIGNALING PROTEIN
1xba  TRANSFERASE
1xbb  TRANSFERASE
1xbc  TRANSFERASE
1xkk  TRANSFERASE
1y57  TRANSFERASE
1y6a  TRANSFERASE
1y6b  TRANSFERASE
1yi6  TRANSFERASE
1yoj  TRANSFERASE
1yol  TRANSFERASE
1yom  TRANSFERASE
1yvj  TRANSFERASE
1ywn  TRANSFERASE
1z3k  STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1zfp  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
2a08  PROTEIN BINDING
2a36  SIGNALING PROTEIN
2a37  SIGNALING PROTEIN
2abl  TRANSFERASE
2aoa  TRANSFERASE
2aob  TRANSFERASE
2aug  SIGNALING PROTEIN
2auh  TRANSFERASE/SIGNALING PROTEIN
2azs  SIGNALING PROTEIN
2azv  SIGNALING PROTEIN
2b3o  HYDROLASE
2b7a  TRANSFERASE
2bdf  TRANSFERASE
2bdj  TRANSFERASE
2c0i  TRANSFERASE
2c0o  TRANSFERASE
2c0t  TRANSFERASE
2ci8  SH2-DOMAIN
2ci9  SH2-DOMAIN/COMPLEX
2cia  SH2-DOMAIN
2cs0  SIGNALING PROTEIN
2d8h  UNKNOWN FUNCTION
2df6  SIGNALING PROTEIN
2dl3  CELL ADHESION, SIGNALING PROTEIN
2dl4  SIGNALING PROTEIN
2dlm  CELL ADHESION
2dly  TRANSFERASE
2dm0  TRANSFERASE
2dq7  TRANSFERASE
2dx0  HYDROLASE
2e2b  TRANSFERASE
2eb2  TRANSFERASE
2eb3  TRANSFERASE
2ecd  SIGNALING PROTEIN
2ecz  SIGNALING PROTEIN
2ekx  SIGNALING PROTEIN
2eo3  SIGNALING PROTEIN
2esw  SIGNALING PROTEIN
2etm  TRANSFERASE
2etz  TRANSFERASE
2eu0  TRANSFERASE
2eva  TRANSFERASE/TRANSFERASE ACTIVATOR
2eyv  SIGNALING PROTEIN
2eyw  SIGNALING PROTEIN
2f4j  TRANSFERASE
2fb8  TRANSFERASE
2fgi  TRANSFERASE
2fo0  TRANSFERASE
2fry  PROTEIN BINDING
2g15  TRANSFERASE
2g1t  TRANSFERASE
2g2f  TRANSFERASE
2g2h  TRANSFERASE
2g2i  TRANSFERASE
2g6f  SIGNALING PROTEIN
2gbq  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
2gqg  TRANSFERASE
2gs2  TRANSFERASE
2gs6  TRANSFERASE
2gs7  TRANSFERASE
2gsf  TRANSFERASE
2h46  HORMONE/GROWTH FACTOR
2h5k  HORMONE/GROWTH FACTOR
2h8h  TRANSFERASE
2hck  TRANSFERASE
2hdv  SIGNALING PROTEIN
2hdx  SIGNALING PROTEIN
2hel  SIGNALING PROTEIN, TRANSFERASE
2hen  TRANSFERASE
2hiw  TRANSFERASE
2hk5  TRANSFERASE
2huw  HORMONE/GROWTH FACTOR
2hwo  TRANSFERASE
2hwp  TRANSFERASE
2hyy  TRANSFERASE
2hz0  TRANSFERASE
2hz4  TRANSFERASE
2hzi  TRANSFERASE
2hzn  TRANSFERASE
2i0v  TRANSFERASE
2i0y  TRANSFERASE
2i1m  TRANSFERASE
2ijm  SIGNALING PROTEIN,TRANSFERASE
2itn  TRANSFERASE
2ito  TRANSFERASE
2itp  TRANSFERASE
2itq  TRANSFERASE
2itt  TRANSFERASE
2itu  TRANSFERASE
2itv  TRANSFERASE
2itw  TRANSFERASE
2itx  TRANSFERASE
2ity  TRANSFERASE
2itz  TRANSFERASE
2ivs  TRANSFERASE
2ivt  TRANSFERASE
2ivu  TRANSFERASE
2ivv  TRANSFERASE
2j0j  TRANSFERASE
2j0k  TRANSFERASE
2j0l  TRANSFERASE
2j0m  TRANSFERASE
2j5e  TRANSFERASE
2j5f  TRANSFERASE
2j6m  TRANSFERASE
2jit  TRANSFERASE
2jiu  TRANSFERASE
2jiv  TRANSFERASE
2jkk  TRANSFERASE
2jkm  TRANSFERASE
2jko  TRANSFERASE
2jkq  TRANSFERASE
2jyq  TRANSFERASE
2o2w  SIGNALING PROTEIN
2o31  SIGNALING PROTEIN
2o9s  SIGNALING PROTEIN
2o9v  SIGNALING PROTEIN/CELL ADHESION
2of2  TRANSFERASE
2of4  TRANSFERASE
2ofu  TRANSFERASE
2ofv  TRANSFERASE
2og8  TRANSFERASE
2ogv  TRANSFERASE
2oh4  TRANSFERASE
2oiq  TRANSFERASE
2oj9  TRANSFERASE
2oo8  TRANSFERASE
2oq1  TRANSFERASE
2osc  TRANSFERASE
2ozo  TRANSFERASE
2p0c  TRANSFERASE
2p2h  TRANSFERASE
2p2i  TRANSFERASE
2p4i  TRANSFERASE
2p4r  LIGASE
2pl0  TRANSFERASE
2psq  TRANSFERASE
2ptk  TYROSINE-PROTEIN KINASE
2pvf  TRANSFERASE
2pvy  TRANSFERASE
2pwl  TRANSFERASE
2py3  TRANSFERASE
2pz5  TRANSFERASE
2pzp  TRANSFERASE
2pzr  TRANSFERASE
2q0b  TRANSFERASE
2qi8  SIGNALING PROTEIN, TRANSFERASE
2qlq  TRANSFERASE
2qms  SIGNALING PROTEIN
2qo2  TRANSFERASE
2qo7  TRANSFERASE
2qo9  TRANSFERASE
2qob  TRANSFERASE
2qoc  TRANSFERASE
2qod  TRANSFERASE
2qof  TRANSFERASE
2qoh  TRANSFERASE
2qoi  TRANSFERASE
2qok  TRANSFERASE
2qol  TRANSFERASE
2qon  TRANSFERASE
2qoo  TRANSFERASE
2qoq  TRANSFERASE
2qq7  TRANSFERASE
2qu5  TRANSFERASE
2qu6  TRANSFERASE
2r2p  TRANSFERASE
2r4b  TRANSFERASE
2rei  TRANSFERASE
2rf9  TRANSFERASE
2rfd  TRANSFERASE
2rfe  TRANSFERASE
2rfn  TRANSFERASE
2rfs  TRANSFERASE
2rgp  TRANSFERASE
2rl5  TRANSFERASE
2rmx  SIGNALING PROTEIN
2src  TYROSINE-PROTEIN KINASE
2v7a  TRANSFERASE
2vif  SIGNALING PROTEIN
2vwu  TRANSFERASE
2vwv  TRANSFERASE
2vww  TRANSFERASE
2vwx  TRANSFERASE
2vwy  TRANSFERASE
2vwz  TRANSFERASE
2vx0  TRANSFERASE
2vx1  TRANSFERASE
2w1i  TRANSFERASE
2ysx  SIGNALING PROTEIN
2yt6  CELL CYCLE
2yu7  SIGNALING PROTEIN
2yup  CELL ADHESION
2z60  TRANSFERASE
2z8c  TRANSFERASE
2zm1  TRANSFERASE
2zm3  TRANSFERASE
2zm4  TRANSFERASE
2zv7  TRANSFERASE
2zv8  TRANSFERASE
2zv9  TRANSFERASE
2zva  TRANSFERASE
2zyb  TRANSFERASE
3b2t  TRANSFERASE
3b2w  TRANSFERASE
3b8q  TRANSFERASE
3b8r  TRANSFERASE
3bbt  TRANSFERASE
3bbw  TRANSFERASE
3bce  TRANSFERASE
3be2  TRANSFERASE
3bea  TRANSFERASE
3bel  TRANSFERASE
3bkb  TRANSFERASE
3bpr  TRANSFERASE
3brb  TRANSFERASE
3bu3  TRANSFERASE
3bu5  TRANSFERASE
3bu6  TRANSFERASE
3bym  TRANSFERASE
3byo  TRANSFERASE
3bys  TRANSFERASE
3byu  TRANSFERASE
3bz3  TRANSFERASE
3c1x  TRANSFERASE
3c4f  TRANSFERASE
3c7q  TRANSFERASE
3cbl  TRANSFERASE
3cc6  TRANSFERASE
3ccn  TRANSFERASE
3cd3  TRANSFERASE
3cd8  TRANSFERASE
3ce3  TRANSFERASE
3cjf  TRANSFERASE
3cjg  TRANSFERASE
3cly  TRANSFERASE
3cp9  TRANSFERASE
3cpb  TRANSFERASE
3cpc  TRANSFERASE
3cs9  TRANSFERASE
3cth  TRANSFERASE
3ctj  TRANSFERASE
3d7t  TRANSFERASE
3d7u  TRANSFERASE
3d94  TRANSFERASE
3dk3  TRANSFERASE
3dk6  TRANSFERASE
3dk7  TRANSFERASE
3dko  TRANSFERASE
3dqw  TRANSFERASE
3dqx  TRANSFERASE
3dtw  TRANSFERASE
3dzq  TRANSFERASE
3e62  TRANSFERASE
3e63  TRANSFERASE
3e64  TRANSFERASE
3efj  TRANSFERASE
3efk  TRANSFERASE
3ekk  TRANSFERASE
3ekn  TRANSFERASE
3el7  TRANSFERASE
3el8  TRANSFERASE
3emg  TRANSFERASE
3en4  TRANSFERASE
3en5  TRANSFERASE
3en6  TRANSFERASE
3en7  TRANSFERASE
3eqp  TRANSFERASE
3eqr  TRANSFERASE
3eyg  TRANSFERASE
3eyh  TRANSFERASE
3f5p  TRANSFERASE
3f66  TRANSFERASE
3f6x  TRANSFERASE
3faa  TRANSFERASE
3fup  TRANSFERASE
3fxx  TRANSFERASE
3fy2  TRANSFERASE
3gbq  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
3hck  TRANSFERASE
3lck  TYROSINE-PROTEIN KINASE
4gbq  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)

PSSH:
ID  Description
Q53EL3  UNKNOWN
P41240  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
124095  CYTOPLASMIC TYROSINE KINASE; CSK   c-SRC TYROSINE KINASE

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0005515  protein binding
GO:0005524  ATP binding
GO:0005737  cytoplasm
GO:0005886  plasma membrane
GO:0005911  cell-cell junction
GO:0006468  protein amino acid phosphorylation
GO:0008022  protein C-terminus binding
GO:0008285  negative regulation of cell proliferation
GO:0016740  transferase activity

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04062  Chemokine signaling pathway
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa04722  Neurotrophin signaling pathway
hsa04810  Regulation of actin cytoskeleton

Panther:
ID  Description
P00053  T cell activation
P00049  Parkinson disease
P00034  Integrin signalling pathway

Chemicals
DrugBank:
ID  Name  Synonyms
DB02010  Staurosporine  
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000103653 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240] Pan_troglodytesone2one ENSPTRG00000007282Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]CSK
Pongo_pygmaeusone2one ENSPPYG00000006646Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Macaca_mulattaone2one ENSMMUG00000015267Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000003060Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Equus_caballusone2one ENSECAG00000013581Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]LOC100051462
Tupaia_belangerione2one ENSTBEG00000006632Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Felis_catusone2one ENSFCAG00000000347Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Tursiops_truncatusone2one ENSTTRG00000007997Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Loxodonta_africanaone2one ENSLAFG00000007435Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Myotis_lucifugusone2one ENSMLUG00000013625Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Otolemur_garnettiione2one ENSOGAG00000005591Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000012946Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Bos_taurusone2one ENSBTAG00000021424Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase). [Source:UniProtKB/Swiss-Prot;Acc:Q0VBZ0][hgnc]CSK
Procavia_capensisone2one ENSPCAG00000002321Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Canis_familiarisone2one ENSCAFG00000017945Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000002772Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Cavia_porcellusone2one ENSCPOG00000003446Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Mus_musculusone2one ENSMUSG00000032312Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase MPK-2) (p50CSK) [Source:UniProtKB/Swiss-Prot;Acc:P41241][hgnc]Csk
Ochotona_princepsone2one ENSOPRG00000010512Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Rattus_norvegicusone2one ENSRNOG00000019374Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase). [Source:UniProtKB/Swiss-Prot;Acc:P32577][hgnc]Csk
Dipodomys_ordiione2one ENSDORG00000013011Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase MPK-2) (p50CSK) [Source:UniProtKB/Swiss-Prot;Acc:P41241][hgnc]
Sorex_araneusone2one ENSSARG00000009659Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Monodelphis_domesticaone2one ENSMODG00000009310Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Gallus_gallusone2one ENSGALG00000001318Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]CSK
Tetraodon_nigroviridisone2many ENSTNIG00000011931Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000014659Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Oryzias_latipesone2many ENSORLG00000014381Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Xenopus_tropicalisone2one ENSXETG00000021139Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Danio_rerioone2many ENSDARG00000067996Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Danio_rerioone2many ENSDARG00000070805c-src tyrosine kinase [Source:RefSeq_peptide;Acc:NP_001071067][hgnc]LOC100000779
Danio_rerioone2many ENSDARG00000051930[hgnc]LOC563480
Gasterosteus_aculeatusone2many ENSGACG00000009794Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Takifugu_rubripesone2one ENSTRUG00000017074Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000016046Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Oryzias_latipesone2many ENSORLG00000004867Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]
Ciona_savignyione2many ENSCSAVG00000003351[hgnc]
Ciona_intestinalismany2many ENSCING00000003438[hgnc]
Ciona_intestinalismany2many ENSCING00000017722[hgnc]