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Summary sheet information for Effector 'Tubulin-Homo sapiens-2'
Name Tubulin-Homo sapiens-2
Description RecName: Full=Tubulin alpha-1B chain;AltName: Full=Tubulin alpha-ubiquitous chain;AltName: Full=Alpha-tubulin ubiquitous;AltName: Full=Tubulin K-alpha-1
Class
Family Tubulins
Sub_family Tubulins
type Tubulin
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 12
Gene Start: 47807836
Gene End: 47811571
Ensembl Contig View

Ensembl Genes:
ENSG00000123416

EMBL:
EMBL ID  Description
AF081484  Homo sapiens alpha-tubulin isoform 1 mRNA, complete cds.
AK289354  Homo sapiens cDNA FLJ78587 complete cds.
BC000696  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:2215 IMAGE:3349131), complete cds.
BC001128  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:2457 IMAGE:2964447), complete cds.
BC001805  Homo sapiens cDNA clone IMAGE:3543670, **** WARNING: chimeric clone ****.
BC006379  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:12832 IMAGE:4100566), complete cds.
BC006481  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:4387 IMAGE:2905305), complete cds.
BC008659  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:9918 IMAGE:3871729), complete cds.
BC009314  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:16616 IMAGE:4111591), complete cds.
BC009509  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:4689 IMAGE:3533174), complete cds.
BC009512  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:4753 IMAGE:3537301), complete cds.
BC009513  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:4760 IMAGE:3537827), complete cds.
BC010494  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:17433 IMAGE:3445903), complete cds.
BC011572  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:20231 IMAGE:4561240), complete cds.
BC015883  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:10192 IMAGE:3909374), complete cds.
BC017004  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:22108 IMAGE:4430457), complete cds.
BC030820  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:23826 IMAGE:4277263), complete cds.
BC071904  Homo sapiens tubulin, alpha 1b, mRNA (cDNA clone MGC:88583 IMAGE:6089096), complete cds.
DQ400107  Homo sapiens alpha tubulin (K-ALPHA-1) mRNA, complete cds.
K00558  human alpha-tubulin mRNA, complete cds.

EntrezGene:
ID  Description
TUBA1B  tubulin, alpha 1b

RefSeq DNA:
ID  Description
NM_006082  Homo sapiens tubulin, alpha 1b (TUBA1B), mRNA.
XR_017548  PREDICTED: Homo sapiens misc_RNA (LOC399942), miscRNA.
XR_018160  PREDICTED: Homo sapiens misc_RNA (LOC399942), miscRNA.
XR_039691  PREDICTED: Homo sapiens misc_RNA (LOC399942), miscRNA.

UniGene:
ID  Description

Proteins
Ensembl Proteins:
ENSP00000336799

Entrez Proteins:
AAA91576.1; AAC31959.1; AAH00696.1; AAH01128.1; AAH01805.1; AAH06379.1; AAH06481.1; AAH08659.1; AAH09314.1; AAH09509.1; AAH09512.1; AAH09513.1; AAH10494.1; AAH11572.1; AAH15883.1; AAH17004.1; AAH30820.1; AAH71904.1; ABD60581.1; BAF82043.1

RefSeq Proteins:
ID  Description
NP_006073  tubulin, alpha, ubiquitous [Homo sapiens].

UniProt:
ID  Description
A8JZY9  SubName: Full=cDNA FLJ78587;
Q9BUX9  UNKNOWN
P68363  RecName: Full=Tubulin alpha-1B chain; AltName: Full=Tubulin alpha-ubiquitous chain; AltName: Full=Alpha-tubulin ubiquitous; AltName: Full=Tubulin K-alpha-1;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Tubulin-Homo sapiens-2    

InterPro:
ID  Name
IPR003008  Tubulin_FtsZ
IPR002452  Alpha_tubulin
IPR017975  Tubulin_CS
IPR000217  Tubulin
IPR008280  Tub_FtsZ_C

Pfam:
ID  Description
Tubulin  Tubulin/FtsZ family, GTPase domain
Tubulin_C  Tubulin/FtsZ family, C-terminal domain

Structure
PDB:
ID
2E4H

HSSP:
ID  Description
1ffx  STRUCTURAL PROTEIN
1ia0  TRANSPORT PROTEIN
1jff  STRUCTURAL PROTEIN
1sa0  CELL CYCLE
1sa1  CELL CYCLE
1tub  MICROTUBULES
1tvk  CELL CYCLE, STRUCTURAL PROTEIN
1z2b  CELL CYCLE
2bto  CYTOSKELETAL PROTEIN
2btq  CYTOSKELETAL PROTEIN/COMPLEX
2hxf  TRANSPORT PROTEIN
2hxh  TRANSPORT PROTEIN
2p4n  TRANSPORT PROTEIN
3dco  MOTOR PROTEIN
3du7  CELL CYCLE
3e22  CELL CYCLE
3edl  STRUCTURAL PROTEIN

PSSH:
ID  Description
P68363  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
602530  TUBULIN, ALPHA-1B; TUBA1B   TUBULIN, ALPHA, UBIQUITOUS K-ALPHA-1

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0003924  GTPase activity
GO:0005198  structural molecule activity
GO:0005525  GTP binding
GO:0005737  cytoplasm
GO:0005874  microtubule
GO:0007017  microtubule-based process
GO:0007018  microtubule-based movement
GO:0043234  protein complex
GO:0051258  protein polymerization

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04540  Gap junction
hsa05130  Pathogenic Escherichia coli infection

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000123416 Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363] Pan_troglodytesone2one ENSPTRG00000012950Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1). [Source:UniProtKB/Swiss-Prot;Acc:Q5R1W4][hgnc]TUBA1B
Macaca_mulattaone2one ENSMMUG00000021081Alpha-tubulin (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q9GLW6][hgnc]
Tursiops_truncatusone2one ENSTTRG00000004794Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Bos_taurusone2one ENSBTAG00000012244Tubulin alpha-ubiquitous chain (Alpha-tubulin ubiquitous) (Tubulin K- alpha-1) (Fragment). [Source:UniProtKB/Swiss-Prot;Acc:P81947][hgnc]TUBA1B
Microcebus_murinusone2one ENSMICG00000017551Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Loxodonta_africanaone2one ENSLAFG00000018666Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000013266Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Otolemur_garnettiione2one ENSOGAG00000013490Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Mus_musculusone2many ENSMUSG00000023004Tubulin alpha-1B chain (Tubulin alpha-2 chain) (Alpha-tubulin 2) (Alpha-tubulin isotype M-alpha-2) [Source:UniProtKB/Swiss-Prot;Acc:P05213][hgnc]Tuba1b
Tupaia_belangerione2one ENSTBEG00000001671Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Oryctolagus_cuniculusone2one ENSOCUG00000004082Alpha-tubulin (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q9GLM9][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000004642Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Dipodomys_ordiione2one ENSDORG00000006812[hgnc]
Rattus_norvegicusapprent_one2one ENSRNOG00000032138tubulin, alpha 1B (Tuba1b), mRNA [Source:RefSeq_dna;Acc:NM_001044270][hgnc]LOC691781
Cavia_porcellusone2one ENSCPOG00000013016Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Mus_musculusone2many ENSMUSG00000056904[hgnc]EG434428
Echinops_telfairione2one ENSETEG00000018118Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Ochotona_princepsone2one ENSOPRG00000014803Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000013030Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Monodelphis_domesticaone2one ENSMODG00000015206Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000007702Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]100092229
Xenopus_tropicalisapprent_one2one ENSXETG00000011185Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Oryzias_latipesone2many ENSORLG00000016464Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Oryzias_latipesone2many ENSORLG00000016016Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Oryzias_latipesone2many ENSORLG00000014148Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000012430Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000011552Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000011524Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000011595Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000011587Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000011345Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000012429Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000012539Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000010436Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000002701Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Takifugu_rubripesone2many ENSTRUG00000014163Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Takifugu_rubripesone2many ENSTRUG00000007865Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000003061Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000004715Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) [Source:UniProtKB/Swiss-Prot;Acc:P68363][hgnc]
Caenorhabditis_elegansone2many C44B11.3mec-12 encodes a novel C. elegans alpha-tubulin that is unique amongst C. elegans alpha tubulins in that it may be subject to post-translational acetylation. MEC-12 is required for normal mechanosensory response to gentle touch, and specifically for formation of the 15-protofilament microtubule bundle present in the touch receptor neurons. mec-12 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis. MEC-12 is highly expressed in the touch neurons as well as in several other neurons that do not contains the microfilament bundle, such as the ventral cord motorneurons. [Source: WormBase][hgnc]mec-12
Saccharomyces_cerevisiaemany2many YML085CTubulin alpha-1 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09733][hgnc]TUB1
Saccharomyces_cerevisiaemany2many YML124CTubulin alpha-3 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09734][hgnc]TUB3