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Summary sheet information for Effector 'Tubulin-Homo sapiens-5'
Name Tubulin-Homo sapiens-5
Description RecName: Full=Tubulin alpha-3E chain;AltName: Full=Alpha-tubulin 3E
Class
Family Tubulins
Sub_family Tubulins
type Tubulin
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 2
Gene Start: 130665790
Gene End: 130672510
Ensembl Contig View

Ensembl Genes:
ENSG00000152086

EMBL:
EMBL ID  Description
BC057811  Homo sapiens tubulin, alpha 3e, mRNA (cDNA clone MGC:71743 IMAGE:5298532), complete cds.

EntrezGene:
ID  Description
TUBA3E  tubulin, alpha 3e

RefSeq DNA:
ID  Description
NM_207312  Homo sapiens tubulin, alpha 3e (TUBA3E), mRNA.

UniGene:
ID  Description
Hs.433336  Tubulin, alpha 3e (TUBA3E), mRNA

Proteins
Ensembl Proteins:
ENSP00000318197

Entrez Proteins:
AAH57811.1

RefSeq Proteins:
ID  Description
NP_997195  tubulin, alpha 3e [Homo sapiens].

UniProt:
ID  Description
Q6PEY2  RecName: Full=Tubulin alpha-3E chain; AltName: Full=Alpha-tubulin 3E;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Tubulin-Homo sapiens-5    

InterPro:
ID  Name
IPR000217  Tubulin
IPR008280  Tub_FtsZ_C
IPR003008  Tubulin_FtsZ
IPR002452  Alpha_tubulin

Pfam:
ID  Description
Tubulin  Tubulin/FtsZ family, GTPase domain
Tubulin_C  Tubulin/FtsZ family, C-terminal domain

Structure
PDB:
ID

HSSP:
ID  Description
1ffx  STRUCTURAL PROTEIN
1ia0  TRANSPORT PROTEIN
1jff  STRUCTURAL PROTEIN
1sa0  CELL CYCLE
1sa1  CELL CYCLE
1tub  MICROTUBULES
1tvk  CELL CYCLE, STRUCTURAL PROTEIN
1z2b  CELL CYCLE
2bto  CYTOSKELETAL PROTEIN
2btq  CYTOSKELETAL PROTEIN/COMPLEX
2hxf  TRANSPORT PROTEIN
2hxh  TRANSPORT PROTEIN
2p4n  TRANSPORT PROTEIN
3dco  MOTOR PROTEIN
3du7  CELL CYCLE
3e22  CELL CYCLE
3edl  STRUCTURAL PROTEIN

PSSH:
ID  Description
Q6PEY2  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0003924  GTPase activity
GO:0005198  structural molecule activity
GO:0005525  GTP binding
GO:0005737  cytoplasm
GO:0005874  microtubule
GO:0007017  microtubule-based process
GO:0007018  microtubule-based movement
GO:0043234  protein complex
GO:0051258  protein polymerization

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04540  Gap junction
hsa05130  Pathogenic Escherichia coli infection

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000152086 Tubulin alpha-3E chain (Alpha-tubulin 3E) [Source:UniProtKB/Swiss-Prot;Acc:Q6PEY2] Pan_troglodytesone2many ENSPTRG00000012467[hgnc]LOC465169
Macaca_mulattaone2many ENSMMUG00000006668[hgnc]
Felis_catusmany2many ENSFCAG00000010749[hgnc]
Felis_catusmany2many ENSFCAG00000003826[hgnc]
Oryctolagus_cuniculusone2many ENSOCUG00000005221[hgnc]
Mus_musculusmany2many ENSMUSG00000067702Tubulin alpha-3 chain (Tubulin alpha-3/alpha-7 chain) (Alpha-tubulin 3/7) (Alpha-tubulin isotype M-alpha-3/7) [Source:UniProtKB/Swiss-Prot;Acc:P05214][hgnc]Tuba3b
Bos_taurusone2many ENSBTAG00000030979Tubulin alpha-3 chain (Alpha-tubulin 3). [Source:UniProtKB/Swiss-Prot;Acc:Q32KN8][hgnc]TUBA3D
Mus_musculusmany2many ENSMUSG00000067338Tubulin alpha-3 chain (Tubulin alpha-3/alpha-7 chain) (Alpha-tubulin 3/7) (Alpha-tubulin isotype M-alpha-3/7) [Source:UniProtKB/Swiss-Prot;Acc:P05214][hgnc]Tuba3b
Sorex_araneusone2many ENSSARG00000009727[hgnc]
Monodelphis_domesticaone2many ENSMODG00000023336[hgnc]
Gallus_gallusone2many ENSGALG00000010439Tubulin alpha-1 chain (Fragment). [Source:UniProtKB/Swiss-Prot;Acc:P02552][hgnc]TUBA3D
Ciona_savignyione2many ENSCSAVG00000009895[hgnc]
Ciona_intestinalismany2many ENSCING00000001070Alpha-tubulin 1 (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q8MVT7][hgnc]
Ciona_intestinalismany2many ENSCING00000008913Alpha-tubulin 1 (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q8MVT7][hgnc]
Ciona_intestinalismany2many ENSCING00000001080Alpha-tubulin 1 (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q8MVT7][hgnc]
Caenorhabditis_elegansone2many C44B11.3mec-12 encodes a novel C. elegans alpha-tubulin that is unique amongst C. elegans alpha tubulins in that it may be subject to post-translational acetylation. MEC-12 is required for normal mechanosensory response to gentle touch, and specifically for formation of the 15-protofilament microtubule bundle present in the touch receptor neurons. mec-12 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis. MEC-12 is highly expressed in the touch neurons as well as in several other neurons that do not contains the microfilament bundle, such as the ventral cord motorneurons. [Source: WormBase][hgnc]mec-12
Saccharomyces_cerevisiaemany2many YML085CTubulin alpha-1 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09733][hgnc]TUB1
Saccharomyces_cerevisiaemany2many YML124CTubulin alpha-3 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09734][hgnc]TUB3