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Summary sheet information for Effector 'Tubulin-Homo sapiens-7'
Name Tubulin-Homo sapiens-7
Description RecName: Full=Putative tubulin-like protein alpha-4B;AltName: Full=Alpha-tubulin 4B
Class
Family Tubulins
Sub_family Tubulins
type Tubulin
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 2
Gene Start: 219839190
Gene End: 219845154
Ensembl Contig View

Ensembl Genes:
ENSG00000163526

EMBL:
EMBL ID  Description
AC068946  Homo sapiens BAC clone RP11-803J6 from 2, complete sequence.
AK024002  Homo sapiens cDNA FLJ13940 fis, clone Y79AA1000833, moderately similar to TUBULIN ALPHA-1 CHAIN.

EntrezGene:
ID  Description

RefSeq DNA:
ID  Description
NR_003063  Homo sapiens tubulin, alpha 4b (pseudogene) (TUBA4B) on chromosome 2.

UniGene:
ID  Description
Hs.664469  CDNA FLJ13940 fis, clone Y79AA1000833, moderately similar to TUBULIN ALPHA-1 CHAIN

Proteins
Ensembl Proteins:
ENSP00000295766

Entrez Proteins:
BAB14767.1

RefSeq Proteins:
ID  Description

UniProt:
ID  Description
Q9H853  RecName: Full=Putative tubulin-like protein alpha-4B; AltName: Full=Alpha-tubulin 4B;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Tubulin-Homo sapiens-7    

InterPro:
ID  Name
IPR008280  Tub_FtsZ_C
IPR002452  Alpha_tubulin
IPR003008  Tubulin_FtsZ
IPR000217  Tubulin

Pfam:
ID  Description
Tubulin  Tubulin/FtsZ family, GTPase domain
Tubulin_C  Tubulin/FtsZ family, C-terminal domain

Structure
PDB:
ID

HSSP:
ID  Description

PSSH:
ID  Description
Q9H853  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
600632  OPIOID-BINDING PROTEIN/CELL ADHESION MOLECULE-LIKE; OPCML   OPIOID-BINDING CELL ADHESION MOLECULE OBCAM

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0003924  GTPase activity
GO:0005198  structural molecule activity
GO:0005525  GTP binding
GO:0005874  microtubule
GO:0007017  microtubule-based process
GO:0007018  microtubule-based movement
GO:0043234  protein complex
GO:0051258  protein polymerization

Pathway
KEGG:
KEGG PATHWAY ID  Name

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000163526 Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853] Pan_troglodytesone2one ENSPTRG00000012447Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Dipodomys_ordiione2one ENSDORG00000000156[hgnc]
Felis_catusone2one ENSFCAG00000011251Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Loxodonta_africanaone2one ENSLAFG00000009055Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000006608Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Vicugna_pacosone2one ENSVPAG00000006096Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Procavia_capensisone2one ENSPCAG00000002517Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000014156Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Myotis_lucifugusone2one ENSMLUG00000008088Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Echinops_telfairione2one ENSETEG00000010297Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Sorex_araneusone2one ENSSARG00000000861Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B) [Source:UniProtKB/Swiss-Prot;Acc:Q9H853][hgnc]
Caenorhabditis_elegansone2many C44B11.3mec-12 encodes a novel C. elegans alpha-tubulin that is unique amongst C. elegans alpha tubulins in that it may be subject to post-translational acetylation. MEC-12 is required for normal mechanosensory response to gentle touch, and specifically for formation of the 15-protofilament microtubule bundle present in the touch receptor neurons. mec-12 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis. MEC-12 is highly expressed in the touch neurons as well as in several other neurons that do not contains the microfilament bundle, such as the ventral cord motorneurons. [Source: WormBase][hgnc]mec-12
Saccharomyces_cerevisiaemany2many YML085CTubulin alpha-1 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09733][hgnc]TUB1
Saccharomyces_cerevisiaemany2many YML124CTubulin alpha-3 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09734][hgnc]TUB3