Quick search:







Summary sheet information for GPCR 'CHEMOKINE RECEPTORS_CMKLR1_Homo sapiens'
Name CHEMOKINE RECEPTORS_CMKLR1_Homo sapiens
Description RecName: Full=Chemokine receptor-like 1;AltName: Full=G-protein coupled receptor DEZ;AltName: Full=G-protein coupled receptor ChemR23
Class CLASS A
Family CHEMOKINE RECEPTORS
Sub_family CMKLR1
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
Expand All Collapse All
Genes
Gene Location:
Chromosome: 12
Gene Start: 107209477
Gene End: 107257220
Ensembl Contig View

Ensembl Genes:
ENSG00000174600

EMBL:
EMBL ID  Description
AB065871  Homo sapiens gene for seven transmembrane helix receptor, complete cds, isolate:CBRC7TM_434.
AB112777  Homo sapiens gpcr mRNA for seven transmembrane helix receptor, complete cds.
AK291800  Homo sapiens cDNA FLJ76668 complete cds, highly similar to Homo sapiens chemokine-like receptor 1, mRNA.
AY497547  Homo sapiens chemokine-like receptor 1 (CMKLR1) mRNA, complete cds.
BC106927  Homo sapiens chemokine-like receptor 1, mRNA (cDNA clone MGC:126105 IMAGE:40033186), complete cds.
BC106928  Homo sapiens chemokine-like receptor 1, mRNA (cDNA clone MGC:126106 IMAGE:40033187), complete cds.
BT019556  Homo sapiens chemokine-like receptor 1 mRNA, complete cds.
BT019557  Homo sapiens chemokine-like receptor 1 mRNA, complete cds.
CH471054  Homo sapiens 211000035840223 genomic scaffold, whole genome shotgun sequence.
U79526  Human orphan G-protein coupled receptor Dez isoform a mRNA, complete cds.
U79527  Human orphan G-protein coupled receptor Dez isoform b mRNA, complete cds.
Y14838  Homo sapiens ChemR23 gene

EntrezGene:
ID  Description
CMKLR1  chemokine-like receptor 1

RefSeq DNA:
ID  Description
NM_004072  Homo sapiens chemokine-like receptor 1 (CMKLR1), transcript variant 2, mRNA.

UniGene:
ID  Description

Proteins
Ensembl Proteins:
ENSP00000311733; ENSP00000380803

Entrez Proteins:
AAC51258.1; AAC51259.1; AAI06928.1; AAI06929.1; AAR90850.1; AAV38363.1; AAV38364.1; BAC06089.1; BAF34667.1; BAF84489.1; CAA75112.1; EAW97810.1; EAW97811.1

RefSeq Proteins:
ID  Description
NP_004063  chemokine-like receptor 1 isoform b [Homo sapiens].

UniProt:
ID  Description
Q99788-2  UNKNOWN
A8K6Y5  SubName: Full=cDNA FLJ76668, highly similar to Homo sapiens chemokine-like receptor 1, mRNA; SubName: Full=HCG1641952, isoform CRA_b;
Q05KQ8  SubName: Full=Seven transmembrane helix receptor;
Q5U0H0  SubName: Full=Chemokine-like receptor 1; SubName: Full=HCG1641952, isoform CRA_a;
Q99788  RecName: Full=Chemokine receptor-like 1; AltName: Full=G-protein coupled receptor DEZ; AltName: Full=G-protein coupled receptor ChemR23;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR002258  DEZorph_rcpt
IPR000276  GPCR_Rhodpsn
IPR001274  C5A_anaphtx_rcpt
IPR017452  GPCR_Rhodpsn_supfam

Pfam:
ID  Description
7tm_1  7 transmembrane receptor (rhodopsin family)

Structure
PDB:
ID

HSSP:
ID  Description

PSSH:
ID  Description

Diseases
OMIM:
OMIM ID  Name  Alt Name
602351  CHEMOKINE-LIKE RECEPTOR 1; CMKLR1   CHEMR23 CHEMERIN RECEPTOR; CHEMERINR

Gene Ontology
GO:
GO ID  Description
GO:0001501  skeletal system development
GO:0001584  rhodopsin-like receptor activity
GO:0004872  receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0004942  anaphylatoxin receptor activity
GO:0004944  C5a anaphylatoxin receptor activity
GO:0004945  angiotensin type II receptor activity
GO:0004947  bradykinin receptor activity
GO:0004950  chemokine receptor activity
GO:0004982  N-formyl peptide receptor activity
GO:0005886  plasma membrane
GO:0005887  integral to plasma membrane
GO:0006935  chemotaxis
GO:0006955  immune response
GO:0007165  signal transduction
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007596  blood coagulation
GO:0015057  thrombin receptor activity
GO:0016021  integral to membrane
GO:0045028  purinergic nucleotide receptor activity, G-protein coupled

Pathway
KEGG:
KEGG PATHWAY ID  Name

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000174600 Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788] Pongo_pygmaeusone2one ENSPPYG00000004917Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Oryctolagus_cuniculusone2one ENSOCUG00000012259Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Equus_caballusone2one ENSECAG00000000946Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]LOC100059916
Tursiops_truncatusone2one ENSTTRG00000007503Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Felis_catusone2one ENSFCAG00000010888Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Ochotona_princepsone2many ENSOPRG00000008820[hgnc]
Ochotona_princepsone2many ENSOPRG00000007309[hgnc]
Vicugna_pacosone2one ENSVPAG00000009764Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000013395Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Loxodonta_africanaone2one ENSLAFG00000018638Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Bos_taurusone2one ENSBTAG00000022039Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]CMKLR1
Otolemur_garnettiione2one ENSOGAG00000004539Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Cavia_porcellusone2one ENSCPOG00000000485Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Rattus_norvegicusone2one ENSRNOG00000000704Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled chemoattractant-like receptor). [Source:UniProtKB/Swiss-Prot;Acc:O35786][hgnc]Cmklr1
Dipodomys_ordiione2one ENSDORG00000005977Chemokine receptor-like 1 (G-protein coupled receptor DEZ) [Source:UniProtKB/Swiss-Prot;Acc:P97468][hgnc]
Mus_musculusone2one ENSMUSG00000042190Chemokine receptor-like 1 (G-protein coupled receptor DEZ) [Source:UniProtKB/Swiss-Prot;Acc:P97468][hgnc]Cmklr1
Dasypus_novemcinctusone2one ENSDNOG00000002457Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000005757Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]100078349
Gallus_gallusone2many ENSGALG00000009696[hgnc]LOC425507
Gallus_gallusone2many ENSGALG00000004854[hgnc]
Xenopus_tropicalisone2one ENSXETG00000011474Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Danio_rerioone2many ENSDARG00000035594chemokine-like receptor 1 [Source:RefSeq_peptide;Acc:NP_001076281][hgnc]cmklr1
Takifugu_rubripesone2many ENSTRUG00000014139Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000008778Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000015865Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Oryzias_latipesone2many ENSORLG00000006867Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Danio_rerioone2many ENSDARG00000024795Novel protein similar to vertebrate formyl peptide receptor 1 (FPR1) (Fragment). [Source:UniProtKB/TrEMBL;Acc:A2BGL4][hgnc]LOC795365
Oryzias_latipesone2many ENSORLG00000008329Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000016979Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000009076Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]
Takifugu_rubripesone2many ENSTRUG00000011395Chemokine receptor-like 1 (G-protein coupled receptor DEZ) (G-protein coupled receptor ChemR23) [Source:UniProtKB/Swiss-Prot;Acc:Q99788][hgnc]