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Summary sheet information for Effector 'ATP-sensitive inward rectifier potassium channel 10-Homo sapiens'
Name ATP-sensitive inward rectifier potassium channel 10-Homo sapiens
Description "RecName: Full=ATP-sensitive inward rectifier potassium channel 10;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 10;AltName: Full=Inward rectifier K(+) channel Kir1.2;AltName: Full=ATP-dependent inwardly rectifying potassium channel Kir4.1;"
Class
Family Ion channels
Sub_family ATP-sensitive inward rectifier potassium channels
type ATP-sensitive inward rectifier potassium channel 10
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 1
Gene Start: 158274657
Gene End: 158306585
Ensembl Contig View

Ensembl Genes:
ENSG00000177807

EMBL:
EMBL ID  Description
AF344826  Homo sapiens inwardly-rectifying potassium channel Kir1.2 (KCNJ10) gene, 5'UTR and partial cds.
AF482710  Homo sapiens potassium inwardly-rectifying channel (KCNJ10) gene, exon 2 and complete cds.
AK312383  Homo sapiens cDNA, FLJ92713, highly similar to Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 10 (KCNJ10), mRNA.
AL513302  Human DNA sequence from clone RP11-226L15 on chromosome 1 Contains a ribosomal protein L27a (RPL27A) pseudogene, the PIGM gene for class M phosphatidylinositol glycan, the 3' end of the KCNJ10 gene for potassium inwardly-rectifying channel subfamily J member 10 and a CpG island.
BC034036  Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 10, mRNA (cDNA clone IMAGE:4811633), partial cds.
BC131627  Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 10, mRNA (cDNA clone MGC:149802 IMAGE:40118533), complete cds.
CH471121  Homo sapiens 211000035830426 genomic scaffold, whole genome shotgun sequence.
U52155  Human ATP-dependent inwardly rectifying potassium channel Kir4.1 mRNA, complete cds.
U73192  Human inward rectifier potassium channel Kir1.2 (Kir1.2) gene, complete cds.
U73193  Human inward rectifier potassium channel Kir1.2 (Kir1.2) mRNA, partial cds.

EntrezGene:
ID  Description
KCNJ10  potassium inwardly-rectifying channel, subfamily J, member 10

RefSeq DNA:
ID  Description
NM_002241  Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 10 (KCNJ10), mRNA.

UniGene:
ID  Description
Hs.408960  Inward rectifier potassium channel Kir1.2 (Kir1.2)
Hs.599538  Transcribed locus
Hs.608212  Transcribed locus

Proteins
Ensembl Proteins:
ENSP00000357068

Entrez Proteins:
AAB07046.1; AAC50923.1; AAC50924.1; AAH34036.2; AAI31628.1; AAK27517.1; AAL89708.1; BAG35301.1; CAH71493.1; EAW52749.1

RefSeq Proteins:
ID  Description
NP_002232  potassium inwardly-rectifying channel, subfamily J, member 10 [Homo sapiens].

UniProt:
ID  Description
A3KME7  SubName: Full=KCNJ10 protein (Potassium inwardly-rectifying channel, subfamily J, member 10, isoform CRA_b);
B2R604  SubName: Full=cDNA, FLJ92713, highly similar to Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 10 (KCNJ10), mRNA;
Q547K1  SubName: Full=Potassium inwardly-rectifying channel;
Q9BXC5  SubName: Full=Inwardly-rectifying potassium channel Kir1.2; Flags: Fragment;
P78508  RecName: Full=ATP-sensitive inward rectifier potassium channel 10; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 10; AltName: Full=Inward rectifier K(+) channel Kir1.2; AltName: Full=ATP-dependent inwardly rectifying potassium channel Kir4.1;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     ATP-sensitive inward rectifier potassium channel 10-Homo sapiens    

InterPro:
ID  Name
IPR001838  K_chnl_inward-rec_Kir-like
IPR013521  K_chnl_inward-rec_Kir_Cr2
IPR013518  K_chnl_inward-rec_Kir_cyto
IPR016449  K_chnl_inward-rec_Kir
IPR003269  K_chnl_inward-rec_Kir1.2

Pfam:
ID  Description
IRK  Inward rectifier potassium channel

Structure
PDB:
ID

HSSP:
ID  Description
1n9p  METAL TRANSPORT
1p7b  METAL TRANSPORT
1u4e  METAL TRANSPORT
1u4f  ALLERGEN
2e4f  TRANSPORT PROTEIN
2gix  METAL TRANSPORT
2qks  METAL TRANSPORT

PSSH:
ID  Description
Q547K1  UNKNOWN
A3KME7  UNKNOWN
P78508  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
602208  POTASSIUM CHANNEL, INWARDLY RECTIFYING, SUBFAMILY J, MEMBER 10; KCNJ10   GLIAL INWARDLY RECTIFYING POTASSIUM CHANNEL Kir4.1

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0005242  inward rectifier potassium channel activity
GO:0005244  voltage-gated ion channel activity
GO:0005267  potassium channel activity
GO:0005515  protein binding
GO:0005524  ATP binding
GO:0005887  integral to plasma membrane
GO:0006811  ion transport
GO:0006813  potassium ion transport
GO:0015272  ATP-activated inward rectifier potassium channel activity
GO:0016020  membrane
GO:0030955  potassium ion binding

Pathway
KEGG:
KEGG PATHWAY ID  Name

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000177807 ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508] Pan_troglodytesone2one ENSPTRG00000030365ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]KCNJ10
Pongo_pygmaeusone2one ENSPPYG00000000644ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Macaca_mulattaone2one ENSMMUG00000009929ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Otolemur_garnettiione2one ENSOGAG00000000856ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Equus_caballusone2one ENSECAG00000004647ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]LOC100058121
Microcebus_murinusone2one ENSMICG00000014939ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Tursiops_truncatusone2one ENSTTRG00000001823ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000005200ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Myotis_lucifugusone2one ENSMLUG00000001230ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000007965ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Bos_taurusone2one ENSBTAG00000002414MGC152173 protein. [Source:UniProtKB/TrEMBL;Acc:A2VDQ4][hgnc]KCNJ10
Oryctolagus_cuniculusone2one ENSOCUG00000011928Kir4.1 (Fragment). [Source:UniProtKB/TrEMBL;Acc:O19044][hgnc]
Dipodomys_ordiione2one ENSDORG00000011681ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1) [Source:UniProtKB/Swiss-Prot;Acc:Q9JM63][hgnc]
Tupaia_belangerione2one ENSTBEG00000006913ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Cavia_porcellusone2one ENSCPOG00000003788ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Mus_musculusone2one ENSMUSG00000044708ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1) [Source:UniProtKB/Swiss-Prot;Acc:Q9JM63][hgnc]LOC677282
Canis_familiarisone2one ENSCAFG00000011871ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]KCNJ10
Rattus_norvegicusone2one ENSRNOG00000007705ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (ATP-sensitive inward rectifier potassium channel KAB-2) (Kir4.1) (BIR10) (Brain- specific inwardly rectifying K(+) channel 1) (BIRK1). [Source:UniProtKB/Swiss-Prot;Acc:P49655][hgnc]Kcnj10
Felis_catusone2one ENSFCAG00000008537ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000007513ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Monodelphis_domesticaone2one ENSMODG00000024584ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Sorex_araneusone2one ENSSARG00000000517ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Xenopus_tropicalisone2one ENSXETG00000019842ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000001787ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Danio_rerioone2one ENSDARG00000014697[hgnc]LOC100003416
Tetraodon_nigroviridisone2many ENSTNIG00000007438ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000018986ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Oryzias_latipesone2one ENSORLG00000002717ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Takifugu_rubripesone2many ENSTRUG00000008764ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000017705ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Takifugu_rubripesone2many ENSTRUG00000001706ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000006226ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) [Source:UniProtKB/Swiss-Prot;Acc:P78508][hgnc]