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Summary sheet information for Effector 'Synembryn(Ric8a)-Homo sapiens'
Name Synembryn(Ric8a)-Homo sapiens
Description RecName: Full=Synembryn-A;AltName: Full=Protein Ric-8A
Class
Family Guanine nucleotide exchange factors
Sub_family Synembryns
type Synembryn(Ric8a)
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 11
Gene Start: 198530
Gene End: 205106
Ensembl Contig View

Ensembl Genes:
ENSG00000177963

EMBL:
EMBL ID  Description
AK022870  Homo sapiens cDNA FLJ12808 fis, clone NT2RP2002373.
AK027090  Homo sapiens cDNA: FLJ23437 fis, clone HRC13266.
AK027461  Homo sapiens cDNA FLJ14555 fis, clone NT2RM2001855.
AL136935  Homo sapiens mRNA; cDNA DKFZp586O0222 (from clone DKFZp586O0222)
AL390088  Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1987170.
BC011821  Homo sapiens resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), mRNA (cDNA clone IMAGE:3688123), partial cds.
BC111499  Homo sapiens resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), mRNA (cDNA clone MGC:131931 IMAGE:6526180), complete cds.
BC121807  Homo sapiens resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), mRNA (cDNA clone MGC:148074 IMAGE:40108083), complete cds.
BC121808  Homo sapiens resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), mRNA (cDNA clone MGC:148073 IMAGE:40108080), complete cds.
BX538115  Homo sapiens mRNA; cDNA DKFZp686O16163 (from clone DKFZp686O16163)

EntrezGene:
ID  Description
RIC8A  resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)

RefSeq DNA:
ID  Description
NM_021932  Homo sapiens resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) (RIC8A), mRNA.

UniGene:
ID  Description
Hs.709344  UNKNOWN

Proteins
Ensembl Proteins:
ENSP00000325941

Entrez Proteins:
AAH11821.2; AAI11500.1; AAI21808.1; AAI21809.1; BAB14282.1; BAB15653.1; BAB55126.1; CAB66869.1; CAB98211.1; CAD98025.1

RefSeq Proteins:
ID  Description
NP_068751  resistance to inhibitors of cholinesterase 8 homolog A [Homo sapiens].

UniProt:
ID  Description
Q9NPQ8-2  UNKNOWN
Q9NPQ8-3  UNKNOWN
Q9NPQ8  RecName: Full=Synembryn-A; AltName: Full=Protein Ric-8A;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR008376  Synembryn

Pfam:
ID  Description

Structure
PDB:
ID

HSSP:
ID  Description

PSSH:
ID  Description

Diseases
OMIM:
OMIM ID  Name  Alt Name
609146  RIC8, C. ELEGANS, HOMOLOG OF, A   RIC8A SYNEMBRYN, C. ELEGANS, HOMOLOG OF, A

Gene Ontology
GO:
GO ID  Description
GO:0001701  in utero embryonic development
GO:0001965  G-protein alpha-subunit binding
GO:0005085  guanyl-nucleotide exchange factor activity
GO:0005096  GTPase activator activity
GO:0005488  binding
GO:0005737  cytoplasm
GO:0008542  visual learning
GO:0009416  response to light stimulus

Pathway
KEGG:
KEGG PATHWAY ID  Name

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000177963 Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8] Pan_troglodytesone2one ENSPTRG00000003104Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]RIC8A
Pongo_pygmaeusone2one ENSPPYG00000019966Synembryn-A (Protein Ric-8A). [Source:UniProtKB/Swiss-Prot;Acc:Q5R8F5][hgnc]
Macaca_mulattaone2one ENSMMUG00000011506Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Microcebus_murinusone2one ENSMICG00000006293Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Otolemur_garnettiione2one ENSOGAG00000003226Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Equus_caballusone2one ENSECAG00000003790Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]LOC100051024
Tursiops_truncatusone2one ENSTTRG00000013525Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Canis_familiarisone2one ENSCAFG00000006439Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]RIC8A
Spermophilus_tridecemlineatusone2one ENSSTOG00000015042Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Bos_taurusone2one ENSBTAG00000002042Synembryn-A (Protein Ric-8A). [Source:UniProtKB/Swiss-Prot;Acc:Q5E9J8][hgnc]RIC8A
Oryctolagus_cuniculusone2one ENSOCUG00000014493Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Felis_catusone2one ENSFCAG00000002667Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000010930Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000017702Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Mus_musculusone2one ENSMUSG00000025485Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q3TIR3][hgnc]Ric8
Dipodomys_ordiione2one ENSDORG00000012088Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q3TIR3][hgnc]
Rattus_norvegicusone2one ENSRNOG00000013256Synembryn-A (Protein Ric-8A). [Source:UniProtKB/Swiss-Prot;Acc:Q80ZG1][hgnc]Ric8a
Myotis_lucifugusone2one ENSMLUG00000008635Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Sorex_araneusone2one ENSSARG00000012669Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Ochotona_princepsone2one ENSOPRG00000008790Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Procavia_capensisone2one ENSPCAG00000004352Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Cavia_porcellusone2one ENSCPOG00000021871Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Gallus_gallusone2one ENSGALG00000004191Synembryn-A (Protein Ric-8A). [Source:UniProtKB/Swiss-Prot;Acc:Q5ZL77][hgnc]RCJMB04_7f5
Ornithorhynchus_anatinusone2one ENSOANG00000022023Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]100089097
Xenopus_tropicalisone2one ENSXETG00000002868Resistance to inhibitors of cholinesterase 8 homolog. [Source:UniProtKB/TrEMBL;Acc:Q6P4W7][hgnc]
Danio_rerioone2many ENSDARG00000007247Synembryn-A (Protein Ric-8A). [Source:UniProtKB/Swiss-Prot;Acc:Q642H7][hgnc]zgc:92294
Danio_rerioone2many ENSDARG00000052093[hgnc]LOC100006450
Oryzias_latipesone2one ENSORLG00000018382Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Gasterosteus_aculeatusone2one ENSGACG00000002515Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Takifugu_rubripesone2many ENSTRUG00000003665Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Takifugu_rubripesone2many ENSTRUG00000017385Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]
Tetraodon_nigroviridisone2one ENSTNIG00000014178Synembryn-A (Protein Ric-8A) [Source:UniProtKB/Swiss-Prot;Acc:Q9NPQ8][hgnc]