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Summary sheet information for Effector 'ATP-sensitive inward rectifier potassium channel 14-Homo sapiens'
Name ATP-sensitive inward rectifier potassium channel 14-Homo sapiens
Description "RecName: Full=ATP-sensitive inward rectifier potassium channel 14;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 14;AltName: Full=Inward rectifier K(+) channel Kir2.4; Short=IRK4;"
Class
Family Ion channels
Sub_family ATP-sensitive inward rectifier potassium channels
type ATP-sensitive inward rectifier potassium channel 14
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 19
Gene Start: 53650578
Gene End: 53661179
Ensembl Contig View

Ensembl Genes:
ENSG00000182324

EMBL:
EMBL ID  Description
AF081466  Homo sapiens inward rectifier potassium channel (KIR2.4) mRNA, complete cds.
AF181988  Homo sapiens inwardly rectifying potassium channel Kir2.4 (KCNJ14) gene, complete cds.
BC035918  Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 14, mRNA (cDNA clone MGC:46111 IMAGE:5531571), complete cds.

EntrezGene:
ID  Description
KCNJ14  potassium inwardly-rectifying channel, subfamily J, member 14

RefSeq DNA:
ID  Description
NM_013348  Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 14 (KCNJ14), transcript variant 1, mRNA.
NM_170720  Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 14 (KCNJ14), transcript variant 2, mRNA.

UniGene:
ID  Description
Hs.590945  Potassium inwardly-rectifying channel, subfamily J, member 14 (KCNJ14), transcript variant 2, mRNA

Proteins
Ensembl Proteins:
ENSP00000341479; ENSP00000375756

Entrez Proteins:
AAD51376.1; AAF97619.1; AAH35918.1

RefSeq Proteins:
ID  Description
NP_037480  potassium inwardly-rectifying channel J14 [Homo sapiens].
NP_733838  potassium inwardly-rectifying channel J14 [Homo sapiens].

UniProt:
ID  Description
Q9UNX9  RecName: Full=ATP-sensitive inward rectifier potassium channel 14; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 14; AltName: Full=Inward rectifier K(+) channel Kir2.4; Short=IRK4;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     ATP-sensitive inward rectifier potassium channel 14-Homo sapiens    

InterPro:
ID  Name
IPR016449  K_chnl_inward-rec_Kir
IPR013518  K_chnl_inward-rec_Kir_cyto
IPR013521  K_chnl_inward-rec_Kir_Cr2
IPR001838  K_chnl_inward-rec_Kir-like

Pfam:
ID  Description
IRK  Inward rectifier potassium channel

Structure
PDB:
ID

HSSP:
ID  Description
1n9p  METAL TRANSPORT
1p7b  METAL TRANSPORT
1u4e  METAL TRANSPORT
1u4f  ALLERGEN
2e4f  TRANSPORT PROTEIN
2gix  METAL TRANSPORT
2qks  METAL TRANSPORT

PSSH:
ID  Description
Q9UNX9  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
603953  POTASSIUM INWARDLY-RECTIFYING CHANNEL, SUBFAMILY J, MEMBER 14; KCNJ14   KIR2.4

Gene Ontology
GO:
GO ID  Description
GO:0005242  inward rectifier potassium channel activity
GO:0005244  voltage-gated ion channel activity
GO:0006811  ion transport
GO:0006813  potassium ion transport
GO:0008076  voltage-gated potassium channel complex
GO:0016020  membrane
GO:0016021  integral to membrane
GO:0030955  potassium ion binding

Pathway
KEGG:
KEGG PATHWAY ID  Name

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000182324 ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9] Caenorhabditis_elegansmany2many R03E9.4Inward rectifier potassium channel irk-1. [Source:UniProtKB/Swiss-Prot;Acc:P52192][hgnc]irk-1
Caenorhabditis_elegansmany2many M02A10.2irk-2 encodes an inwardly rectifying potassium channel based on sequence homology to the the human potassium channel genes KCNJ1/KCNJ2. [Source: WormBase][hgnc]irk-2
Aedes_aegyptimany2many AAEL008931inwardly rectifying k+ channel,[hgnc]
Aedes_aegyptimany2many AAEL013373inwardly rectifying k+ channel,[hgnc]
Anopheles_gambiaemany2many AGAP001284[hgnc]AgaP_ENSANGG00000024811
Pan_troglodytesone2one ENSPTRG00000011237ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]KCNJ14
Macaca_mulattaone2one ENSMMUG00000001792ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000003748ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Tupaia_belangerione2one ENSTBEG00000010667ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Canis_familiarisone2one ENSCAFG00000004001ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]KCNJ14
Equus_caballusone2one ENSECAG00000009854ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000008338ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Microcebus_murinusone2one ENSMICG00000008901ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Bos_taurusone2one ENSBTAG00000000082ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]KCNJ14
Loxodonta_africanaone2one ENSLAFG00000007497ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000001986ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Oryctolagus_cuniculusone2one ENSOCUG00000008998ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Cavia_porcellusone2one ENSCPOG00000002292Inwardly-rectifying potassium channel Kir2.4. [Source:UniProtKB/TrEMBL;Acc:Q9EP58][hgnc]
Procavia_capensisone2one ENSPCAG00000003348ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Otolemur_garnettiione2one ENSOGAG00000005700ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Myotis_lucifugusone2one ENSMLUG00000014869ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Echinops_telfairione2one ENSETEG00000013240ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Spermophilus_tridecemlineatusone2one ENSSTOG00000000271ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Tursiops_truncatusone2one ENSTTRG00000007871ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Ochotona_princepsone2one ENSOPRG00000013111ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Mus_musculusone2one ENSMUSG00000058743ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q8JZN3][hgnc]Kcnj14
Rattus_norvegicusone2one ENSRNOG00000021056ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q8JZN3][hgnc]
Sorex_araneusone2one ENSSARG00000002114ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Dipodomys_ordiione2one ENSDORG00000012823ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q8JZN3][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000008163ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]100092312
Xenopus_tropicalisone2one ENSXETG00000004575ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Gasterosteus_aculeatusone2one ENSGACG00000011616ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Oryzias_latipesone2one ENSORLG00000010708ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Takifugu_rubripesone2one ENSTRUG00000015539ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Tetraodon_nigroviridisone2one ENSTNIG00000008074ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4) [Source:UniProtKB/Swiss-Prot;Acc:Q9UNX9][hgnc]
Aedes_aegyptimany2many AAEL008932inwardly rectifying k+ channel,[hgnc]
Drosophila_melanogastermany2many FBgn0039061[hgnc]Ir
Anopheles_gambiaemany2many AGAP001280[hgnc]AgaP_ENSANGG00000017854
Drosophila_melanogastermany2many FBgn0039081[hgnc]Irk2
Aedes_aegyptimany2many AAEL008928inwardly rectifying k+ channel,[hgnc]
Anopheles_gambiaemany2many AGAP001283[hgnc]AgaP_ENSANGG00000017795
Anopheles_gambiaemany2many AGAP001281[hgnc]AgaP_ENSANGG00000020396