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Summary sheet information for Effector 'Tubulin-Homo sapiens-8'
Name Tubulin-Homo sapiens-8
Description RecName: Full=Tubulin alpha-8 chain;AltName: Full=Alpha-tubulin 8;AltName: Full=Tubulin alpha chain-like 2
Class
Family Tubulins
Sub_family Tubulins
type Tubulin
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 22
Gene Start: 16973453
Gene End: 16994498
Ensembl Contig View

Ensembl Genes:
ENSG00000183785

EMBL:
EMBL ID  Description
AJ245922  Homo sapiens mRNA for alpha-tubulin 8 (TUBA8 gene)
AK315316  Homo sapiens cDNA, FLJ96348, Homo sapiens tubulin, alpha 8 (TUBA8), mRNA.
BC074827  Homo sapiens tubulin, alpha 8, mRNA (cDNA clone MGC:104090 IMAGE:30915541), complete cds.
BC104845  Homo sapiens tubulin, alpha 8, mRNA (cDNA clone MGC:132505 IMAGE:8143848), complete cds.
BX537702  Homo sapiens mRNA; cDNA DKFZp686L04275 (from clone DKFZp686L04275)
CH471193  Homo sapiens 211000035831636 genomic scaffold, whole genome shotgun sequence.
CR456600  Homo sapiens TUBA8 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.TUBA8.V2)

EntrezGene:
ID  Description
TUBA8  tubulin, alpha 8

RefSeq DNA:
ID  Description
NM_018943  Homo sapiens tubulin, alpha 8 (TUBA8), mRNA.

UniGene:
ID  Description

Proteins
Ensembl Proteins:
ENSP00000333326; ENSP00000318575

Entrez Proteins:
AAH74827.1; AAI04846.1; BAG37719.1; CAB88036.1; CAD97815.1; CAG30486.1; EAW57788.1

RefSeq Proteins:
ID  Description
NP_061816  tubulin, alpha 8 [Homo sapiens].

UniProt:
ID  Description
B2RCX2  SubName: Full=cDNA, FLJ96348, Homo sapiens tubulin, alpha 8 (TUBA8), mRNA (Tubulin, alpha 8, isoform CRA_a);
Q7Z3M3  SubName: Full=Putative uncharacterized protein DKFZp686L04275; Flags: Fragment;
Q9NY65  RecName: Full=Tubulin alpha-8 chain; AltName: Full=Alpha-tubulin 8; AltName: Full=Tubulin alpha chain-like 2;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR017975  Tubulin_CS
IPR008280  Tub_FtsZ_C
IPR002452  Alpha_tubulin
IPR000217  Tubulin
IPR003008  Tubulin_FtsZ

Pfam:
ID  Description
Tubulin  Tubulin/FtsZ family, GTPase domain
Tubulin_C  Tubulin/FtsZ family, C-terminal domain

Structure
PDB:
ID

HSSP:
ID  Description
1ffx  STRUCTURAL PROTEIN
1ia0  TRANSPORT PROTEIN
1jff  STRUCTURAL PROTEIN
1sa0  CELL CYCLE
1sa1  CELL CYCLE
1tub  MICROTUBULES
1tvk  CELL CYCLE, STRUCTURAL PROTEIN
1z2b  CELL CYCLE
2bto  CYTOSKELETAL PROTEIN
2btq  CYTOSKELETAL PROTEIN/COMPLEX
2hxf  TRANSPORT PROTEIN
2hxh  TRANSPORT PROTEIN
2p4n  TRANSPORT PROTEIN
3dco  MOTOR PROTEIN
3du7  CELL CYCLE
3e22  CELL CYCLE
3edl  STRUCTURAL PROTEIN

PSSH:
ID  Description
Q7Z3M3  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
605742  TUBULIN, ALPHA-8; TUBA8   TUBULIN, ALPHA-LIKE 2; TUBAL2

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0003924  GTPase activity
GO:0005198  structural molecule activity
GO:0005525  GTP binding
GO:0005737  cytoplasm
GO:0005874  microtubule
GO:0007017  microtubule-based process
GO:0007018  microtubule-based movement
GO:0043234  protein complex
GO:0051258  protein polymerization

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04540  Gap junction
hsa05130  Pathogenic Escherichia coli infection

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
DB01873  Epothilone D  KOS-862; epothilone D
DB03010  Epothilone B  EPO 906; EPO906; patupilone
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000183785 Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65] Pan_troglodytesone2one ENSPTRG00000014047Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]TUBA8
Macaca_mulattaone2one ENSMMUG00000014140Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Microcebus_murinusone2one ENSMICG00000017239Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Equus_caballusone2one ENSECAG00000013982Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]LOC100054576
Otolemur_garnettiione2one ENSOGAG00000005974Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Spermophilus_tridecemlineatusone2one ENSSTOG00000012333Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Oryctolagus_cuniculusone2one ENSOCUG00000009387Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Ochotona_princepsone2one ENSOPRG00000015328Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Myotis_lucifugusone2one ENSMLUG00000002951Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Felis_catusone2one ENSFCAG00000009946Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Canis_familiarisone2one ENSCAFG00000016243Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]TUBA8
Procavia_capensisone2one ENSPCAG00000001869Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Tupaia_belangerione2one ENSTBEG00000011890Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Echinops_telfairione2one ENSETEG00000011390Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000002850Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Cavia_porcellusone2one ENSCPOG00000002793Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Mus_musculusone2one ENSMUSG00000030137Tubulin alpha-8 chain (Alpha-tubulin 8) [Source:UniProtKB/Swiss-Prot;Acc:Q9JJZ2][hgnc]Tuba8
Dasypus_novemcinctusone2one ENSDNOG00000003362Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Sorex_araneusone2one ENSSARG00000001346Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Bos_taurusone2one ENSBTAG00000018530Tubulin alpha-8 chain (Alpha-tubulin 8). [Source:UniProtKB/Swiss-Prot;Acc:Q2HJB8][hgnc]TUBA8
Monodelphis_domesticaone2one ENSMODG00000018466Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Gallus_gallusone2many ENSGALG00000013056Tubulin alpha-4 chain (Fragment). [Source:UniProtKB/Swiss-Prot;Acc:P09643][hgnc]TUBA1B
Gallus_gallusone2many ENSGALG00000013045Tubulin alpha-2 chain (Testis-specific). [Source:UniProtKB/Swiss-Prot;Acc:P08070][hgnc]TUBA8
Danio_rerioapprent_one2one ENSDARG00000042708tubulin, alpha 8 like [Source:RefSeq_peptide;Acc:NP_997937][hgnc]tuba8l
Xenopus_tropicalisone2one ENSXETG00000001752Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Takifugu_rubripesone2one ENSTRUG00000006844Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Oryzias_latipesone2one ENSORLG00000015000Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Tetraodon_nigroviridisone2one ENSTNIG00000012477Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NY65][hgnc]
Rattus_norvegicusapprent_one2one ENSRNOG00000028339Tubulin alpha-8 chain (Alpha-tubulin 8) [Source:UniProtKB/Swiss-Prot;Acc:Q9JJZ2][hgnc]
Saccharomyces_cerevisiaemany2many YML085CTubulin alpha-1 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09733][hgnc]TUB1
Saccharomyces_cerevisiaemany2many YML124CTubulin alpha-3 chain. [Source:UniProtKB/Swiss-Prot;Acc:P09734][hgnc]TUB3