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Summary sheet information for GPCR 'NEUROPEPTIDE Y RECEPTORS_Y2_Homo sapiens'
Name NEUROPEPTIDE Y RECEPTORS_Y2_Homo sapiens
Description RecName: Full=Neuropeptide Y receptor type 2; Short=NPY2-R;AltName: Full=NPY-Y2 receptor; Short=Y2 receptor
Class CLASS A
Family NEUROPEPTIDE Y RECEPTORS
Sub_family Y2
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 4
Gene Start: 156349231
Gene End: 156357677
Ensembl Contig View

Ensembl Genes:
ENSG00000185149

EMBL:
EMBL ID  Description
AC104407  Homo sapiens BAC clone RP11-92A5 from 4, complete sequence.
AY236540  Homo sapiens neuropeptide Y receptor Y2 (NPY2R) gene, complete cds.
BC075052  Homo sapiens neuropeptide Y receptor Y2, mRNA (cDNA clone MGC:103963 IMAGE:30915364), complete cds.
BC075053  Homo sapiens neuropeptide Y receptor Y2, mRNA (cDNA clone MGC:104126 IMAGE:30915580), complete cds.
CH471056  Homo sapiens 211000035843078 genomic scaffold, whole genome shotgun sequence.
U32500  Human type 2 neuropeptide Y receptor mRNA, complete cds.
U36269  Human neuropeptide Y/peptide YY Y2 receptor mRNA, complete cds.
U42389  human neuropeptide y/peptide YY receptor type 2 mRNA, complete cds.
U42766  Human neuropeptide y2 receptor mRNA, complete cds.
U50146  Human type 2 neuropeptide Y receptor (NPY Y2) gene, partial exon 2, and complete cds.
U76254  Human neuropeptide Y receptor type 2 gene, complete cds.

EntrezGene:
ID  Description
NPY2R  neuropeptide Y receptor Y2

RefSeq DNA:
ID  Description
NM_000910  Homo sapiens neuropeptide Y receptor Y2 (NPY2R), mRNA.

UniGene:
ID  Description
Hs.37125  Neuropeptide y/peptide YY receptor type 2

Proteins
Ensembl Proteins:
ENSP00000377426; ENSP00000332591

Entrez Proteins:
AAA93170.1; AAB04120.1; AAB07760.1; AAC50281.1; AAC51115.1; AAD00248.1; AAH75052.2; AAH75053.2; AAO92062.1; AAY40940.1; EAX04901.1

RefSeq Proteins:
ID  Description
NP_000901  neuropeptide Y receptor Y2 [Homo sapiens].

UniProt:
ID  Description
Q4W5G7  SubName: Full=Putative uncharacterized protein NPY2R (Neuropeptide Y receptor Y2);
P49146  RecName: Full=Neuropeptide Y receptor type 2; Short=NPY2-R; AltName: Full=NPY-Y2 receptor; Short=Y2 receptor;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR001358  NPY2_rcpt
IPR017452  GPCR_Rhodpsn_supfam
IPR001220  Lectin_legB
IPR000611  NPY_rcpt
IPR000276  GPCR_Rhodpsn

Pfam:
ID  Description
7tm_1  7 transmembrane receptor (rhodopsin family)

Structure
PDB:
ID
2IK3

HSSP:
ID  Description

PSSH:
ID  Description
Q4W5G7  UNKNOWN
P49146  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
162642  NEUROPEPTIDE Y RECEPTOR Y2; NPY2R   UNKNOWN

Gene Ontology
GO:
GO ID  Description
GO:0001584  rhodopsin-like receptor activity
GO:0001601  peptide YY receptor activity
GO:0004872  receptor activity
GO:0004945  angiotensin type II receptor activity
GO:0004983  neuropeptide Y receptor activity
GO:0005246  calcium channel regulator activity
GO:0005529  sugar binding
GO:0005886  plasma membrane
GO:0005887  integral to plasma membrane
GO:0007165  signal transduction
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling
GO:0007601  visual perception
GO:0007626  locomotory behavior
GO:0008188  neuropeptide receptor activity
GO:0015232  heme transporter activity
GO:0015886  heme transport
GO:0016020  membrane
GO:0016021  integral to membrane
GO:0017004  cytochrome complex assembly

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04080  Neuroactive ligand-receptor interaction

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000185149 Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146] Pan_troglodytesone2one ENSPTRG00000016539Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor). [Source:UniProtKB/Swiss-Prot;Acc:Q5IS62][hgnc]NPY2R
Pongo_pygmaeusone2one ENSPPYG00000015282Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Macaca_mulattaone2one ENSMMUG00000014185Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor). [Source:UniProtKB/Swiss-Prot;Acc:Q9GK74][hgnc]574149
Microcebus_murinusone2one ENSMICG00000006281Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000004555Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Equus_caballusone2one ENSECAG00000003978Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]LOC100062115
Tursiops_truncatusone2one ENSTTRG00000006111Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000017812Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Loxodonta_africanaone2one ENSLAFG00000011630Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Bos_taurusone2one ENSBTAG00000016633Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor). [Source:UniProtKB/Swiss-Prot;Acc:P79113][hgnc]NPY2R
Myotis_lucifugusone2one ENSMLUG00000010894Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Ochotona_princepsone2one ENSOPRG00000000396Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Mus_musculusone2one ENSMUSG00000028004Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P97295][hgnc]Npy2r
Cavia_porcellusone2one ENSCPOG00000012625Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R). [Source:UniProtKB/Swiss-Prot;Acc:Q9Z2D5][hgnc]
Rattus_norvegicusone2many ENSRNOG00000030525Neuropeptide Y-Y2 receptor (Fragment). [Source:UniProtKB/TrEMBL;Acc:O70424][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000013584Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Sorex_araneusone2one ENSSARG00000000252Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Monodelphis_domesticaone2one ENSMODG00000024959Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000015672Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]100075224
Tupaia_belangerione2one ENSTBEG00000007167Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Gallus_gallusone2one ENSGALG00000009280Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor). [Source:UniProtKB/Swiss-Prot;Acc:Q9DDN6][hgnc]NPY2R
Danio_rerioone2many ENSDARG00000057718[hgnc]LOC795311
Tetraodon_nigroviridisone2one ENSTNIG00000007120Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Oryzias_latipesone2one ENSORLG00000002440Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Takifugu_rubripesone2one ENSTRUG00000005990Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Gasterosteus_aculeatusapprent_one2one ENSGACG00000018324Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]
Danio_rerioone2many ENSDARG00000037277[hgnc]LOC100003852
Xenopus_tropicalisapprent_one2one ENSXETG00000027979Neuropeptide Y receptor type 2 (NPY-Y2 receptor) (NPY2-R) [Source:UniProtKB/Swiss-Prot;Acc:P49146][hgnc]