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Summary sheet information for Effector 'Tubulin-Homo sapiens-14'
Name Tubulin-Homo sapiens-14
Description RecName: Full=Tubulin beta-2C chain;AltName: Full=Tubulin beta-2 chain
Class
Family Tubulins
Sub_family Tubulins
type Tubulin
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 9
Gene Start: 139255532
Gene End: 139257980
Ensembl Contig View

Ensembl Genes:
ENSG00000188229

EMBL:
EMBL ID  Description
AY167990  Homo sapiens class IVb beta tubulin mRNA, complete cds.
BC001911  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:2666 IMAGE:3544236), complete cds.
BC002783  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:4028 IMAGE:3614023), complete cds.
BC002885  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:11278 IMAGE:3944735), complete cds.
BC004188  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:2826 IMAGE:2964559), complete cds.
BC007889  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:14233 IMAGE:4127195), complete cds.
BC008006  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone IMAGE:3508410), partial cds.
BC012835  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:4826 IMAGE:3603755), complete cds.
BC019359  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:13231 IMAGE:4024979), complete cds.
BC019829  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:29954 IMAGE:5110038), complete cds.
BC024038  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:10845 IMAGE:3616531), complete cds.
BC029529  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:33915 IMAGE:5274343), complete cds.
BC039175  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:21910 IMAGE:4385885), complete cds.
BC071889  Homo sapiens tubulin, beta 2C, mRNA (cDNA clone MGC:88568 IMAGE:4905049), complete cds.
BX255925  Human DNA sequence from clone RP13-122B23 on chromosome 9
EF036499  Homo sapiens tubulin beta 2C mRNA, partial cds.
X02344  Homo sapiens beta 2 gene

EntrezGene:
ID  Description
TUBB2C  tubulin, beta 2C

RefSeq DNA:
ID  Description
NM_006088  Homo sapiens tubulin, beta 2C (TUBB2C), mRNA.

UniGene:
ID  Description
Hs.594600  Transcribed locus, strongly similar to NP_954525.1 tubulin, beta 2c [Rattus norvegicus]

Proteins
Ensembl Proteins:
ENSP00000341289

Entrez Proteins:
AAH01911.1; AAH02783.1; AAH02885.1; AAH04188.1; AAH07889.1; AAH08006.1; AAH12835.1; AAH19359.1; AAH19829.1; AAH24038.1; AAH29529.1; AAH39175.1; AAH71889.1; AAN87335.1; ABO65085.1; CAA26203.1; CAM24148.1

RefSeq Proteins:
ID  Description
NP_006079  tubulin, beta, 2 [Homo sapiens].

UniProt:
ID  Description
A2BFA2  UNKNOWN
A4UCT2  SubName: Full=Tubulin beta 2C; Flags: Fragment;
Q8IWP6  SubName: Full=Class IVb beta tubulin;
Q8IZ29  SubName: Full=Tubulin, beta 2C;
Q8N6N5  SubName: Full=Tubulin, beta 2C;
Q96HX0  SubName: Full=TUBB2C protein; Flags: Fragment;
P68371  RecName: Full=Tubulin beta-2C chain; AltName: Full=Tubulin beta-2 chain;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Tubulin-Homo sapiens-14    

InterPro:
ID  Name
IPR000158  Cell_division_FtsZ_N
IPR000217  Tubulin
IPR013838  Beta-tubulin_BS
IPR008280  Tub_FtsZ_C
IPR002453  Beta_tubulin
IPR017975  Tubulin_CS
IPR003008  Tubulin_FtsZ

Pfam:
ID  Description
Tubulin  Tubulin/FtsZ family, GTPase domain
Tubulin_C  Tubulin/FtsZ family, C-terminal domain

Structure
PDB:
ID

HSSP:
ID  Description
1ffx  STRUCTURAL PROTEIN
1ia0  TRANSPORT PROTEIN
1jff  STRUCTURAL PROTEIN
1sa0  CELL CYCLE
1tub  MICROTUBULES
1tvk  CELL CYCLE, STRUCTURAL PROTEIN
1z2b  CELL CYCLE
1z5v  STRUCTURAL PROTEIN
1z5w  STRUCTURAL PROTEIN
2btq  CYTOSKELETAL PROTEIN/COMPLEX
2hxf  TRANSPORT PROTEIN
2hxh  TRANSPORT PROTEIN
2p4n  TRANSPORT PROTEIN
3cb2  STRUCTURAL PROTEIN, HYDROLASE
3dco  MOTOR PROTEIN
3du7  CELL CYCLE
3e22  CELL CYCLE
3edl  STRUCTURAL PROTEIN

PSSH:
ID  Description
Q8IWP6  UNKNOWN
Q8IZ29  UNKNOWN
Q8N6N5  UNKNOWN
Q96HX0  UNKNOWN
A2BFA2  UNKNOWN
A4UCT2  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
602660  TUBULIN, BETA-2   UNKNOWN

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0003924  GTPase activity
GO:0005198  structural molecule activity
GO:0005525  GTP binding
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005874  microtubule
GO:0006928  cell motion
GO:0007017  microtubule-based process
GO:0007018  microtubule-based movement
GO:0042267  natural killer cell mediated cytotoxicity
GO:0042288  MHC class I protein binding
GO:0043234  protein complex
GO:0051082  unfolded protein binding
GO:0051258  protein polymerization

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04540  Gap junction
hsa05130  Pathogenic Escherichia coli infection

Panther:
ID  Description
P00016  Cytoskeletal regulation by Rho GTPase
P00029  Huntington disease

Chemicals
DrugBank:
ID  Name  Synonyms
DB03010  Epothilone B  EPO 906; EPO906; patupilone
DB01873  Epothilone D  KOS-862; epothilone D
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000188229 Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371] Pan_troglodytesone2one ENSPTRG00000023373Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]TUBB2C
Macaca_mulattaone2one ENSMMUG00000012164Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Pongo_pygmaeusone2one ENSPPYG00000019822Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Microcebus_murinusone2one ENSMICG00000010939Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Cavia_porcellusone2one ENSCPOG00000011966Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Rattus_norvegicusone2one ENSRNOG00000010170Tubulin beta-2C chain. [Source:UniProtKB/Swiss-Prot;Acc:Q6P9T8][hgnc]Tubb2c
Pteropus_vampyrusone2one ENSPVAG00000008384Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Mus_musculusone2one ENSMUSG00000036752Tubulin beta-2C chain [Source:UniProtKB/Swiss-Prot;Acc:P68372][hgnc]100044717
Bos_taurusone2one ENSBTAG00000025274Tubulin beta-2C chain. [Source:UniProtKB/Swiss-Prot;Acc:Q3MHM5][hgnc]TUBB2C
Procavia_capensisone2one ENSPCAG00000004829Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Dasypus_novemcinctusapprent_one2one ENSDNOG00000010566Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Sorex_araneusapprent_one2one ENSSARG00000014150Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Echinops_telfairiapprent_one2one ENSETEG00000014383Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Ochotona_princepsapprent_one2one ENSOPRG00000015941Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Dipodomys_ordiiapprent_one2one ENSDORG00000009430Tubulin beta-2C chain [Source:UniProtKB/Swiss-Prot;Acc:P68372][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000004061Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]100077354
Otolemur_garnettiiapprent_one2one ENSOGAG00000007498Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Tarsius_syrichtaapprent_one2one ENSTSYG00000012371Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Monodelphis_domesticaone2one ENSMODG00000017213Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Drosophila_melanogastermany2many FBgn0003889[hgnc]betaTub85D
Erinaceus_europaeusapprent_one2one ENSEEUG00000004443Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Drosophila_melanogastermany2many FBgn0003887[hgnc]betaTub56D
Ciona_intestinalisone2many ENSCING00000007589[hgnc]
Ciona_savignyione2many ENSCSAVG00000004683[hgnc]
Anopheles_gambiaeone2many AGAP010929[hgnc]AgaP_ENSANGG00000010545
Xenopus_tropicalisone2one ENSXETG00000023413Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Aedes_aegyptione2many AAEL002851tubulin beta chain[hgnc]
Oryctolagus_cuniculusapprent_one2one ENSOCUG00000006608Tubulin beta-2C chain (Tubulin beta-2 chain) [Source:UniProtKB/Swiss-Prot;Acc:P68371][hgnc]
Saccharomyces_cerevisiaeone2many YFL037WTubulin beta chain (Beta-tubulin). [Source:UniProtKB/Swiss-Prot;Acc:P02557][hgnc]TUB2