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Summary sheet information for Effector 'Src tyrosine kinase-Homo sapiens-2'
Name Src tyrosine kinase-Homo sapiens-2
Description RecName: Full=Proto-oncogene tyrosine-protein kinase Src; EC=2.7.10.2;AltName: Full=pp60c-src; Short=p60-Src; Short=c-Src
Class
Family Tyr protein kinases
Sub_family Tyr protein kinases
type Src tyrosine kinase
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 20
Gene Start: 35407971
Gene End: 35467867
Ensembl Contig View

Ensembl Genes:
ENSG00000197122

EMBL:
EMBL ID  Description
AF077754  Homo sapiens tyrosine kinase pp60c-src (SRC) gene, exon 12 and partial cds.
AK024281  Homo sapiens cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to Rattus norvegicus tyrosine protein kinase pp60-c-src mRNA.
AL133293  Human DNA sequence from clone RP5-823N20 on chromosome 20 Contains the 5' end of the SRC gene for v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, the RPL7AL4 gene for ribosomal protein L7A-like 4 (pseudogene) and a CpG island.
BC011566  Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), mRNA (cDNA clone MGC:20184 IMAGE:4548399), complete cds.
BC051270  Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), mRNA (cDNA clone MGC:59921 IMAGE:4871614), complete cds.
CH471077  Homo sapiens 211000035835434 genomic scaffold, whole genome shotgun sequence.
K03212  Human c-src-1 proto-oncogene, exon 6.
K03213  Human c-src-1 proto-oncogene, exon 7.
K03214  Human c-src-1 proto-oncogene, exon 8.
K03215  Human c-src-1 proto-oncogene, exon 9.
K03216  Human c-src-1 proto-oncogene, exon 10.
K03217  Human c-src-1 proto-oncogene, exon 11.
K03218  Human c-src-1 proto-oncogene, exon 12.
M16237  Human c-src-1 proto-oncogene, exon 2.
M16243  Human c-src-1 proto-oncogene, exon 3.
M16244  Human c-src-1 proto-oncogene, exon 4.
M16245  Human c-src-1 proto-oncogene, exon 5.
X02647  Human c-src gene exon 6 (and joined CDS)
X03995  Human c-src gene exon 7
X03996  Human c-src gene exon 8
X03997  Human c-src gene exon 9
X03998  Human c-src gene exon 10
X03999  Human c-src gene exon 11
X04000  Human c-src gene exon 12

EntrezGene:
ID  Description
SRC  v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

RefSeq DNA:
ID  Description
NM_005417  Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 1, mRNA.
NM_198291  Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 2, mRNA.

UniGene:
ID  Description
Hs.195659  5' non-coding end of the c-Src proto-oncogene
Hs.597733  Transcribed locus
Hs.675407  Transcribed locus

Proteins
Ensembl Proteins:
ENSP00000362659; ENSP00000362668; ENSP00000362680; ENSP00000350941; ENSP00000353950

Entrez Proteins:
AAA60584.1; AAC29427.1; AAH11566.1; AAH51270.2; BAB14871.1; CAA26485.1; CAC10573.1; CAC34523.1; EAW76065.1

RefSeq Proteins:
ID  Description
NP_005408  proto-oncogene tyrosine-protein kinase SRC [Homo sapiens].
NP_938033  proto-oncogene tyrosine-protein kinase SRC [Homo sapiens].

UniProt:
ID  Description
P12931-2  UNKNOWN
Q71UK5  SubName: Full=Tyrosine kinase pp60c-src; Flags: Fragment;
Q76P87  SubName: Full=V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Avian) (V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Avian), isoform CRA_d);
Q9H7V3  SubName: Full=cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to Rattus norvegicus tyrosine protein kinase pp60-c-src mRNA;
P12931  RecName: Full=Proto-oncogene tyrosine-protein kinase Src; EC=2.7.10.2; AltName: Full=pp60c-src; Short=p60-Src; Short=c-Src;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Src tyrosine kinase-Homo sapiens-2    

InterPro:
ID  Name
IPR008266  Tyr_pkinase_AS
IPR001245  Tyr_pkinase
IPR001452  SH3_domain
IPR017441  Protein_kinase_ATP_bd_CS
IPR000719  Prot_kinase_core
IPR000980  SH2

Pfam:
ID  Description
SH2  SH2 domain
SH3_1  SH3 domain
Pkinase_Tyr  Protein tyrosine kinase

Structure
PDB:
ID
1A07
1A08
1A09
1A1A
1A1B
1A1C
1A1E
1FMK
1HCS
1HCT
1KSW
1O41
1O42
1O43
1O44
1O45
1O46
1O47
1O48
1O49
1O4A
1O4B
1O4C
1O4D
1O4E
1O4F
1O4G
1O4H
1O4I
1O4J
1O4K
1O4L
1O4M
1O4N
1O4O
1O4P
1O4Q
1O4R
1SHD
1Y57
1YI6
1YOJ
1YOL
1YOM
2BDF
2BDJ
2H8H
2SRC

HSSP:
ID  Description
1a07  COMPLEX (TRANSFERASE/PEPTIDE)
1a08  COMPLEX (TRANSFERASE/PEPTIDE)
1a09  COMPLEX (TRANSFERASE/PEPTIDE)
1a0n  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1a1a  COMPLEX (TRANSFERASE/PEPTIDE)
1a1b  COMPLEX (TRANSFERASE/PEPTIDE)
1a1c  COMPLEX (TRANSFERASE/PEPTIDE)
1a1e  COMPLEX (TRANSFERASE/PEPTIDE)
1a81  COMPLEX (TRANSFERASE/PEPTIDE)
1ab2  TRANSFERASE(PHOSPHOTRANSFERASE)
1abo  COMPLEX (KINASE/PEPTIDE)
1abq  KINASE
1ad5  TYROSINE-PROTEIN KINASE
1aey  CYTOSKELETON
1agw  PROTEIN KINASE
1aot  COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN)
1aou  COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN)
1avz  COMPLEX (MYRISTYLATION/TRANSFERASE)
1awo  KINASE
1aww  TRANSFERASE
1awx  TRANSFERASE
1aya  HYDROLASE(SH2 DOMAIN)
1ayb  HYDROLASE(SH2 DOMAIN)
1ayc  HYDROLASE(SH2 DOMAIN)
1ayd  HYDROLASE(SH2 DOMAIN)
1azg  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1b07  SH3 DOMAIN
1bbz  COMPLEX (TRANSFERASE/PEPTIDE)
1bfi  SH2 DOMAIN
1bfj  SH2 DOMAIN
1bhf  COMPLEX (SH2 DOMAIN/INHIBITOR)
1bhh  SH2 DOMAIN
1bk2  SH3-DOMAIN
1bkl  V-SRC SH2 DOMAIN
1bkm  TRANSFORMING PROTEIN
1blj  PHOSPHORYLATION
1blk  PHOSPHORYLATION
1bm2  HORMONE/GROWTH FACTOR
1bmb  HORMONE/GROWTH FACTOR
1bu1  TRANSFERASE
1byg  TRANSFERASE
1cj1  SIGNALING PROTEIN
1cka  COMPLEX (ONCOGENE PROTEIN/PEPTIDE)
1ckb  COMPLEX (ONCOGENE PROTEIN/PEPTIDE)
1csk  PHOSPHOTRANSFERASE
1csy  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1csz  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1cwd  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1cwe  COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)
1d1z  GENE REGULATION
1e6g  SH3-DOMAIN
1efn  COMPLEX (SH3 DOMAIN/VIRAL ENHANCER)
1f1w  TRANSFERASE
1f2f  TRANSFERASE
1fbz  TRANSFERASE
1fgi  PROTEIN KINASE
1fgk  PHOSPHOTRANSFERASE
1fhs  SH2 DOMAIN
1fmk  PHOSPHOTRANSFERASE
1fpu  TRANSFERASE
1fu5  PEPTIDE BINDING PROTEIN
1fu6  PROTEIN BINDING
1fvr  TRANSFERASE
1fyn  TRANSFERASE
1fyr  HORMONE/GROWTH FACTOR
1g2b  METAL BINDING PROTEIN
1g83  TRANSFERASE
1gag  TRANSFERASE, SIGNALING PROTEIN
1ghu  SRC HOMOLOGY 2 DOMAIN
1gjo  TRANSFERASE
1gl5  TRANSFERASE
1h3h  COMPLEX (SH3/PEPTIDE)
1h92  TRANSFERASE
1h9o  COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR)
1hcs  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1hct  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1hd3  CYTOSKELETON
1hsq  PHOSPHORIC DIESTER HYDROLASE
1i3z  SIGNALING PROTEIN
1i44  TRANSFERASE
1ias  TRANSFERASE
1iep  TRANSFERASE
1ijr  TRANSFERASE/SIGNALING PROTEIN
1ir3  COMPLEX (TRANSFERASE/SUBSTRATE)
1irk  TRANSFERASE (PHOSPHOTRANSFERASE)
1is0  TRANSFERASE
1jeg  TRANSFERASE/HYDROLASE
1jpa  TRANSFERASE
1jqh  TRANSFERASE
1jqq  PROTEIN TRANSPORT, MEMBRANE PROTEIN
1ju5  PROTEIN BINDING/TRANSFERASE
1jwo  TRANSFERASE
1jyq  SIGNALING PROTEIN
1jyr  SIGNALING PROTEIN
1jyu  SIGNALING PROTEIN
1k2p  TRANSFERASE
1k3a  TRANSFERASE
1k9a  TRANSFERASE
1kc2  TRANSFERASE
1kik  TRANSFERASE
1ksw  TRANSFERASE
1lcj  COMPLEX (KINASE/PEPTIDE)
1lck  COMPLEX (KINASE/PEPTIDE)
1lkk  COMPLEX (TYROSINE KINASE/PEPTIDE)
1lkl  COMPLEX (TYROSINE KINASE/PEPTIDE)
1luf  TRANSFERASE
1lui  TRANSFERASE
1luk  TRANSFERASE
1lum  TRANSFERASE
1lun  TRANSFERASE
1m14  TRANSFERASE
1m17  TRANSFERASE
1m27  SIGNALING PROTEIN, TRANSFERASE
1m30  PROTEIN BINDING
1m3a  PROTEIN BINDING
1m3b  PROTEIN BINDING
1m3c  PROTEIN BINDING
1m52  TRANSFERASE
1m7n  TRANSFERASE
1m8m  STRUCTURAL PROTEIN
1mil  TRANSFORMING PROTEIN
1mp8  TRANSFERASE
1mqb  TRANSFERASE
1mw4  HORMONE/GROWTH FACTOR/TRANSFERASE
1n5z  PROTEIN TRANSPORT
1nlo  COMPLEX (TRANSFERASE/PEPTIDE)
1nlp  COMPLEX (TRANSFERASE/PEPTIDE)
1nm7  PROTEIN TRANSPORT
1nyf  PHOSPHOTRANSFERASE
1nyg  PHOSPHOTRANSFERASE
1nzl  TRANSFERASE
1nzv  TRANSFERASE
1o41  SIGNALING PROTEIN
1o42  SIGNALING PROTEIN
1o43  SIGNALING PROTEIN
1o44  SIGNALING PROTEIN
1o45  SIGNALING PROTEIN
1o46  SIGNALING PROTEIN
1o47  SIGNALING PROTEIN
1o48  SIGNALING PROTEIN
1o49  SIGNALING PROTEIN
1o4a  SIGNALING PROTEIN
1o4b  SIGNALING PROTEIN
1o4c  SIGNALING PROTEIN
1o4d  SIGNALING PROTEIN
1o4e  SIGNALING PROTEIN
1o4f  SIGNALING PROTEIN
1o4g  SIGNALING PROTEIN
1o4h  SIGNALING PROTEIN
1o4i  SIGNALING PROTEIN
1o4j  SIGNALING PROTEIN
1o4k  SIGNALING PROTEIN
1o4l  SIGNALING PROTEIN
1o4m  SIGNALING PROTEIN
1o4n  SIGNALING PROTEIN
1o4o  SIGNALING PROTEIN
1o4p  SIGNALING PROTEIN
1o4q  SIGNALING PROTEIN
1o4r  SIGNALING PROTEIN
1oeb  SH3 DOMAIN/COMPLEX
1oec  TRANSFERASE
1oo3  PROTEIN BINDING
1oo4  PROTEIN BINDING
1opj  TRANSFERASE
1opk  TRANSFERASE
1opl  TRANSFERASE
1p13  TRANSFERASE
1p14  TRANSFERASE
1p4o  HORMONE/GROWTH FACTOR
1pic  COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR)
1pkg  TRANSFERASE ACTIVATOR
1prl  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1prm  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1pwt  CIRCULAR PERMUTANT
1qcf  TYROSINE KINASE
1qg1  HORMONE/GROWTH FACTOR
1qkw  CYTOSKELETON
1qkx  CYTOSKELETON
1qly  TYROSINE-PROTEIN KINASE
1qpc  TRANSFERASE
1qpd  TRANSFERASE
1qpe  TRANSFERASE
1qpj  TRANSFERASE
1qwe  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1qwf  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1r0p  TRANSFERASE
1rja  TRANSFERASE
1rjb  TRANSFERASE
1rlp  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1rlq  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1rqq  TRANSFERASE/SIGNALING PROTEIN
1sha  PHOSPHOTRANSFERASE
1shb  PHOSPHOTRANSFERASE
1shd  COMPLEX(TRANSFERASE/PEPTIDE)
1shf  PHOSPHOTRANSFERASE
1shg  CYTOSKELETON
1skj  TYROSINE-PROTEIN KINASE
1sm2  TRANSFERASE
1snu  TRANSFERASE
1snx  TRANSFERASE
1spr  TRANSFERASE(PHOSPHOTRANSFERASE)
1sps  TRANSFERASE(PHOSPHOTRANSFERASE)
1srl  PHOSPHOTRANSFERASE
1srm  PHOSPHOTRANSFERASE
1t45  TRANSFERASE ACTIVATOR
1t46  TRANSFERASE ACTIVATOR
1tce  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1tud  CYTOSKELETON
1tze  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1u46  TRANSFERASE
1u4d  TRANSFERASE
1u54  TRANSFERASE
1u59  TRANSFERASE
1udl  ENDOCYTOSIS/EXOCYTOSIS
1uhc  STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1uhf  SIGNALING PROTEIN
1uti  SH3 DOMAIN/COMPLEX
1uue  SH3-DOMAIN
1uwh  KINASE
1uwj  KINASE
1vjy  TRANSFERASE
1vr2  TRANSFERASE
1w1f  SH3-DOMAIN
1wa7  SH3 DOMAIN
1wxu  PROTEIN TRANSPORT
1x0n  PEPTIDE BINDING PROTEIN
1x27  SIGNALING PROTEIN
1x2k  SIGNALING PROTEIN
1x2p  TRANSFERASE
1xba  TRANSFERASE
1xbb  TRANSFERASE
1xbc  TRANSFERASE
1xkk  TRANSFERASE
1y57  TRANSFERASE
1yi6  TRANSFERASE
1yoj  TRANSFERASE
1yol  TRANSFERASE
1yom  TRANSFERASE
1ywn  TRANSFERASE
1z3k  STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1zbj  TRANSFERASE
1zfp  COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
1zlm  SIGNALING PROTEIN
1zsg  TRANSFERASE
2a08  PROTEIN BINDING
2a37  SIGNALING PROTEIN
2abl  TRANSFERASE
2ak5  ENDOCYTOSIS/EXOCYTOSIS
2aoa  TRANSFERASE
2aob  TRANSFERASE
2aug  SIGNALING PROTEIN
2auh  TRANSFERASE/SIGNALING PROTEIN
2azv  SIGNALING PROTEIN
2bdf  TRANSFERASE
2bdj  TRANSFERASE
2c0i  TRANSFERASE
2c0o  TRANSFERASE
2c0t  TRANSFERASE
2c9w  TRANSCRIPTION REGULATION
2cdt  STRUCTURAL PROTEIN
2cia  SH2-DOMAIN
2cuc  SIGNALING PROTEIN
2cud  SIGNALING PROTEIN
2d0n  SIGNALING PROTEIN
2d8h  UNKNOWN FUNCTION
2d8j  TRANSFERASE
2df6  SIGNALING PROTEIN
2dly  TRANSFERASE
2dlz  SIGNALING PROTEIN
2dm0  TRANSFERASE
2dq7  TRANSFERASE
2dx0  HYDROLASE
2e2b  TRANSFERASE
2eb2  TRANSFERASE
2eb3  TRANSFERASE
2ecd  SIGNALING PROTEIN
2ekx  SIGNALING PROTEIN
2eo3  SIGNALING PROTEIN
2eob  HYDROLASE
2eqi  IMMUNE SYSTEM, HYDROLASE
2esw  SIGNALING PROTEIN
2etm  TRANSFERASE
2etz  TRANSFERASE
2eu0  TRANSFERASE
2eva  TRANSFERASE/TRANSFERASE ACTIVATOR
2eyv  SIGNALING PROTEIN
2eyw  SIGNALING PROTEIN
2f2v  SIGNALING PROTEIN
2f2w  SIGNALING PROTEIN
2f4j  TRANSFERASE
2fb8  TRANSFERASE
2fgi  TRANSFERASE
2fo0  TRANSFERASE
2fry  PROTEIN BINDING
2g15  TRANSFERASE
2g1t  TRANSFERASE
2g2f  TRANSFERASE
2g2h  TRANSFERASE
2g2i  TRANSFERASE
2g6f  SIGNALING PROTEIN
2ge9  TRANSFERASE
2gqg  TRANSFERASE
2gs2  TRANSFERASE
2gs6  TRANSFERASE
2gs7  TRANSFERASE
2gsf  TRANSFERASE
2h46  HORMONE/GROWTH FACTOR
2h5k  HORMONE/GROWTH FACTOR
2h8h  TRANSFERASE
2hck  TRANSFERASE
2hda  TRANSFERASE
2hel  SIGNALING PROTEIN, TRANSFERASE
2hen  TRANSFERASE
2hiw  TRANSFERASE
2hk5  TRANSFERASE
2hsp  PHOSPHORIC DIESTER HYDROLASE
2huw  HORMONE/GROWTH FACTOR
2hwo  TRANSFERASE
2hwp  TRANSFERASE
2hyy  TRANSFERASE
2hz0  TRANSFERASE
2hz4  TRANSFERASE
2hzi  TRANSFERASE
2hzn  TRANSFERASE
2i0v  TRANSFERASE
2i0y  TRANSFERASE
2i1m  TRANSFERASE
2iim  SIGNALING PROTEIN
2ijm  SIGNALING PROTEIN,TRANSFERASE
2itn  TRANSFERASE
2ito  TRANSFERASE
2itp  TRANSFERASE
2itq  TRANSFERASE
2itu  TRANSFERASE
2itw  TRANSFERASE
2itx  TRANSFERASE
2ity  TRANSFERASE
2itz  TRANSFERASE
2iug  TRANSFERASE
2iui  TRANSFERASE
2ivs  TRANSFERASE
2ivt  TRANSFERASE
2ivu  TRANSFERASE
2ivv  TRANSFERASE
2j0j  TRANSFERASE
2j0k  TRANSFERASE
2j0l  TRANSFERASE
2j0m  TRANSFERASE
2j5e  TRANSFERASE
2j5f  TRANSFERASE
2j6m  TRANSFERASE
2jkk  TRANSFERASE
2jkm  TRANSFERASE
2jko  TRANSFERASE
2jkq  TRANSFERASE
2jm8  STRUCTURAL PROTEIN
2jm9  STRUCTURAL PROTEIN
2jma  STRUCTURAL PROTEIN
2js2  SIGNALING PROTEIN
2jw4  SIGNALING PROTEIN
2jyq  TRANSFERASE
2o88  SIGNALING PROTEIN
2of2  TRANSFERASE
2of4  TRANSFERASE
2ofu  TRANSFERASE
2ofv  TRANSFERASE
2og8  TRANSFERASE
2ogv  TRANSFERASE
2oh4  TRANSFERASE
2oi3  TRANSFERASE
2oiq  TRANSFERASE
2oj2  SIGNALING PROTEIN,TRANSFERASE/INHIBITOR
2oj9  TRANSFERASE
2oo8  TRANSFERASE
2osc  TRANSFERASE
2ozo  TRANSFERASE
2p0c  TRANSFERASE
2p2h  TRANSFERASE
2p4i  TRANSFERASE
2p4r  LIGASE
2pl0  TRANSFERASE
2pna  SIGNALLING PROTEIN
2pnb  SIGNALLING PROTEIN
2pqh  STRUCTURAL PROTEIN
2psq  TRANSFERASE
2ptk  TYROSINE-PROTEIN KINASE
2pvf  TRANSFERASE
2pvy  TRANSFERASE
2pwl  TRANSFERASE
2py3  TRANSFERASE
2q0b  TRANSFERASE
2qi8  SIGNALING PROTEIN, TRANSFERASE
2qlq  TRANSFERASE
2qms  SIGNALING PROTEIN
2qo2  TRANSFERASE
2qo7  TRANSFERASE
2qo9  TRANSFERASE
2qob  TRANSFERASE
2qoc  TRANSFERASE
2qod  TRANSFERASE
2qof  TRANSFERASE
2qoh  TRANSFERASE
2qoi  TRANSFERASE
2qok  TRANSFERASE
2qol  TRANSFERASE
2qon  TRANSFERASE
2qoo  TRANSFERASE
2qoq  TRANSFERASE
2qq7  TRANSFERASE
2qu5  TRANSFERASE
2qu6  TRANSFERASE
2r2p  TRANSFERASE
2r4b  TRANSFERASE
2rei  TRANSFERASE
2rf0  TRANSFERASE
2rf9  TRANSFERASE
2rfs  TRANSFERASE
2rgp  TRANSFERASE
2rl5  TRANSFERASE
2rmo  SIGNALING PROTEIN
2src  TYROSINE-PROTEIN KINASE
2v1r  PROTEIN TRANSPORT
2v7a  TRANSFERASE
2vkn  MEMBRANE PROTEIN
2vwu  TRANSFERASE
2vwv  TRANSFERASE
2vww  TRANSFERASE
2vwx  TRANSFERASE
2vwy  TRANSFERASE
2vwz  TRANSFERASE
2vx0  TRANSFERASE
2vx1  TRANSFERASE
2ysx  SIGNALING PROTEIN
2yt6  CELL CYCLE
2z60  TRANSFERASE
2z8c  TRANSFERASE
2zm1  TRANSFERASE
2zm3  TRANSFERASE
2zm4  TRANSFERASE
2zv7  TRANSFERASE
2zv8  TRANSFERASE
2zv9  TRANSFERASE
2zva  TRANSFERASE
2zyb  TRANSFERASE
3b2t  TRANSFERASE
3b2w  TRANSFERASE
3b8r  TRANSFERASE
3bbt  TRANSFERASE
3bbw  TRANSFERASE
3bce  TRANSFERASE
3be2  TRANSFERASE
3bea  TRANSFERASE
3bel  TRANSFERASE
3bkb  TRANSFERASE
3bpr  TRANSFERASE
3brb  TRANSFERASE
3bu3  TRANSFERASE
3bu5  TRANSFERASE
3bu6  TRANSFERASE
3bym  TRANSFERASE
3byo  TRANSFERASE
3bys  TRANSFERASE
3byu  TRANSFERASE
3bz3  TRANSFERASE
3c4c  TRANSFERASE
3c4d  TRANSFERASE
3c4f  TRANSFERASE
3c7i  SPLICING
3c7q  TRANSFERASE
3cbl  TRANSFERASE
3cc6  TRANSFERASE
3ccn  TRANSFERASE
3cd3  TRANSFERASE
3cd8  TRANSFERASE
3cjf  TRANSFERASE
3cjg  TRANSFERASE
3cly  TRANSFERASE
3cpb  TRANSFERASE
3cpc  TRANSFERASE
3cqt  TRANSFERASE
3cs9  TRANSFERASE
3d4q  TRANSFERASE
3d7t  TRANSFERASE
3d7u  TRANSFERASE
3d94  TRANSFERASE
3dk3  TRANSFERASE
3dk6  TRANSFERASE
3dk7  TRANSFERASE
3dko  TRANSFERASE
3dqw  TRANSFERASE
3dqx  TRANSFERASE
3dzq  TRANSFERASE
3efk  TRANSFERASE
3ekk  TRANSFERASE
3ekn  TRANSFERASE
3el7  TRANSFERASE
3el8  TRANSFERASE
3emg  TRANSFERASE
3en4  TRANSFERASE
3en5  TRANSFERASE
3en6  TRANSFERASE
3en7  TRANSFERASE
3eqp  TRANSFERASE
3eqr  TRANSFERASE
3eyg  TRANSFERASE
3eyh  TRANSFERASE
3f5p  TRANSFERASE
3f66  TRANSFERASE
3f6x  TRANSFERASE
3faa  TRANSFERASE
3fxx  TRANSFERASE
3fy2  TRANSFERASE
3hck  TRANSFERASE
3lck  TYROSINE-PROTEIN KINASE
4hck  TRANSFERASE
5hck  TRANSFERASE

PSSH:
ID  Description
Q71UK5  UNKNOWN
Q76P87  UNKNOWN
Q9H7V3  UNKNOWN
P12931  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
190090  V-SRC AVIAN SARCOMA (SCHMIDT-RUPPIN A-2) VIRAL ONCOGENE; SRC   ONCOGENE SRC PROTOONCOGENE SRC SRC ONCOGENE AVIAN SARCOMA VIRUS; ASV

Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0001101  response to acid
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0005070  SH3/SH2 adaptor activity
GO:0005515  protein binding
GO:0005524  ATP binding
GO:0005829  cytosol
GO:0005886  plasma membrane
GO:0005901  caveola
GO:0006468  protein amino acid phosphorylation
GO:0006950  response to stress
GO:0007172  signal complex assembly
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0007243  protein kinase cascade
GO:0007265  Ras protein signal transduction
GO:0008022  protein C-terminus binding
GO:0008283  cell proliferation
GO:0016301  kinase activity
GO:0016337  cell-cell adhesion
GO:0016477  cell migration
GO:0016740  transferase activity
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0019904  protein domain specific binding
GO:0030900  forebrain development
GO:0042169  SH2 domain binding
GO:0043065  positive regulation of apoptosis
GO:0044419  interspecies interaction between organisms
GO:0045056  transcytosis
GO:0045785  positive regulation of cell adhesion
GO:0046628  positive regulation of insulin receptor signaling pathway
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0048011  nerve growth factor receptor signaling pathway
GO:0051385  response to mineralocorticoid stimulus

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04520  Adherens junction
hsa04144  Endocytosis
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa04012  ErbB signaling pathway
hsa04510  Focal adhesion
hsa04540  Gap junction
hsa04912  GnRH signaling pathway
hsa04530  Tight junction
hsa04370  VEGF signaling pathway

Panther:
ID  Description
P00049  Parkinson disease
P00034  Integrin signalling pathway
P00012  Cadherin signaling pathway
P00005  Angiogenesis

Chemicals
DrugBank:
ID  Name  Synonyms
DB01962  Phosphonotyrosine  
DB04739  4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE  
DB01254  Dasatinib  BMS-354825; dasatinib
DB01678  RU84687  N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide
DB04751  Purvalanol A  6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine; Purv
DB01893  N6-Benzyl Adenosine-5'-Diphosphate  
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000197122 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931] Pan_troglodytesone2one ENSPTRG00000013474Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]SRC
Pongo_pygmaeusone2one ENSPPYG00000010985Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Macaca_mulattaone2one ENSMMUG00000020131Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Microcebus_murinusone2one ENSMICG00000005684Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Myotis_lucifugusone2one ENSMLUG00000004480Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Tursiops_truncatusone2one ENSTTRG00000005695Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000017785Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Felis_catusone2one ENSFCAG00000006991Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Bos_taurusone2one ENSBTAG00000008938Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]SRC
Cavia_porcellusone2one ENSCPOG00000011012Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Procavia_capensisone2one ENSPCAG00000005712Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Canis_familiarisone2one ENSCAFG00000008755Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]SRC
Echinops_telfairione2one ENSETEG00000007521Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000005742Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Equus_caballusone2one ENSECAG00000012072Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Otolemur_garnettiione2one ENSOGAG00000015510Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Ochotona_princepsone2one ENSOPRG00000012428Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Dipodomys_ordiione2one ENSDORG00000016279Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P05480][hgnc]
Mus_musculusone2one ENSMUSG00000027646Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P05480][hgnc]Src
Rattus_norvegicusone2one ENSRNOG00000009495Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src). [Source:UniProtKB/Swiss-Prot;Acc:Q9WUD9][hgnc]Src
Gallus_gallusone2one ENSGALG00000003855Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src). [Source:UniProtKB/Swiss-Prot;Acc:P00523][hgnc]SRC
Monodelphis_domesticaone2one ENSMODG00000000247Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Xenopus_tropicalisone2one ENSXETG00000017318C-src tyrosine kinase. [Source:UniProtKB/TrEMBL;Acc:Q5MAS9][hgnc]
Danio_rerioone2one ENSDARG00000008107protein-tyrosine kinase [Source:RefSeq_peptide;Acc:NP_001003837][hgnc]LOC555652
Gasterosteus_aculeatusone2many ENSGACG00000011349Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Oryzias_latipesone2many ENSORLG00000016183Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Takifugu_rubripesone2many ENSTRUG00000005980Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000019527Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000005548Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000018270Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Oryzias_latipesone2many ENSORLG00000006714Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]
Takifugu_rubripesone2many ENSTRUG00000018366Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]