Quick search:







Summary sheet information for GPCR 'NEUROPEPTIDE Y RECEPTORS_Y4_Homo sapiens'
Name NEUROPEPTIDE Y RECEPTORS_Y4_Homo sapiens
Description RecName: Full=Neuropeptide Y receptor type 4; Short=NPY4-R;AltName: Full=Pancreatic polypeptide receptor 1; Short=PP1
Class CLASS A
Family NEUROPEPTIDE Y RECEPTORS
Sub_family Y4
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
Expand All Collapse All
Genes
Gene Location:
Chromosome: 10
Gene Start: 46503540
Gene End: 46508326
Ensembl Contig View

Ensembl Genes:
ENSG00000204174

EMBL:
EMBL ID  Description
AL390716  Human DNA sequence from clone RP11-314P12 on chromosome 10 Contains the PPYR1 gene for Pancreatic polypeptide receptor 1, a novel gene, part of a novel gene and a heterogeneous nuclear ribonucleoprotein A1 (HNRPA1) pseudogene.
AY268432  Homo sapiens pancreatic polypeptide receptor 1 (PPYR1) gene, complete cds.
AY649985  Homo sapiens chromosome 10 pancreatic polypeptide receptor 1 (PPYR1) mRNA, complete cds, alternatively spliced.
AY649986  Homo sapiens chromosome 10 pancreatic polypeptide receptor 1 (PPYR1) mRNA, complete cds, alternatively spliced.
BC096238  Homo sapiens pancreatic polypeptide receptor 1, mRNA (cDNA clone MGC:116895 IMAGE:40005502), complete cds.
BC099637  Homo sapiens pancreatic polypeptide receptor 1, mRNA (cDNA clone MGC:116897 IMAGE:40005506), complete cds.
CR541950  Homo sapiens full open reading frame cDNA clone RZPDo834D1234D for gene PPYR1, pancreatic polypeptide receptor 1; complete cds, without stopcodon.
U35232  Human neuropeptide Y4 receptor protein gene, complete cds.
U42387  Human pancreatic polypeptide receptor mRNA, complete cds.
Z66526  H.sapiens pancreatic polypeptide receptor PP1 gene

EntrezGene:
ID  Description
PPYR1  pancreatic polypeptide receptor 1

RefSeq DNA:
ID  Description
NM_005972  Homo sapiens pancreatic polypeptide receptor 1 (PPYR1), mRNA.

UniGene:
ID  Description
Hs.524719  Pancreatic polypeptide receptor

Proteins
Ensembl Proteins:
ENSP00000379066; ENSP00000363431

Entrez Proteins:
AAB07759.1; AAC50280.1; AAH96238.1; AAH99637.1; AAP23199.1; AAV68196.1; AAV68197.1; CAA91433.1; CAG46748.1; CAI13318.1

RefSeq Proteins:
ID  Description
NP_005963  pancreatic polypeptide receptor 1 [Homo sapiens].

UniProt:
ID  Description
Q4KKW2  SubName: Full=Pancreatic polypeptide receptor 1;
Q5T2X9  SubName: Full=Pancreatic polypeptide receptor 1;
Q6FH06  UNKNOWN
P50391  RecName: Full=Neuropeptide Y receptor type 4; Short=NPY4-R; AltName: Full=Pancreatic polypeptide receptor 1; Short=PP1;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR000276  GPCR_Rhodpsn
IPR000611  NPY_rcpt
IPR017452  GPCR_Rhodpsn_supfam
IPR001933  NPY4_rcpt

Pfam:
ID  Description
7tm_1  7 transmembrane receptor (rhodopsin family)

Structure
PDB:
ID
2IK5

HSSP:
ID  Description

PSSH:
ID  Description
Q4KKW2  UNKNOWN
Q5T2X9  UNKNOWN
Q6FH06  UNKNOWN

Diseases
OMIM:
OMIM ID  Name  Alt Name
601790  PANCREATIC POLYPEPTIDE RECEPTOR 1; PPYR1   Y4 NPY4R PP1

Gene Ontology
GO:
GO ID  Description
GO:0001584  rhodopsin-like receptor activity
GO:0001601  peptide YY receptor activity
GO:0001602  pancreatic polypeptide receptor activity
GO:0004872  receptor activity
GO:0004945  angiotensin type II receptor activity
GO:0004946  bombesin receptor activity
GO:0004983  neuropeptide Y receptor activity
GO:0005886  plasma membrane
GO:0005887  integral to plasma membrane
GO:0007165  signal transduction
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007586  digestion
GO:0007631  feeding behavior
GO:0008015  blood circulation
GO:0016021  integral to membrane

Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04080  Neuroactive ligand-receptor interaction

Panther:
ID  Description

Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000204174 Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391] Pongo_pygmaeusone2one ENSPPYG00000002234Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Pan_troglodytesone2one ENSPTRG00000029894Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]PPYR1
Macaca_mulattaone2one ENSMMUG00000013445Neuropeptide Y receptor 4. [Source:UniProtKB/TrEMBL;Acc:Q6YHV0][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000014434Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Microcebus_murinusone2one ENSMICG00000002979Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000018174Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Equus_caballusone2one ENSECAG00000004222Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]LOC100052105
Myotis_lucifugusone2one ENSMLUG00000002953Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Tursiops_truncatusone2one ENSTTRG00000013553Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Vicugna_pacosone2one ENSVPAG00000002858Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Cavia_porcellusone2one ENSCPOG00000006445Pancreatic polypeptide receptor Y4. [Source:UniProtKB/TrEMBL;Acc:Q9Z2D4][hgnc]
Canis_familiarisone2one ENSCAFG00000016102Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]PPYR1
Oryctolagus_cuniculusone2one ENSOCUG00000014188Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Ochotona_princepsone2one ENSOPRG00000010106Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Bos_taurusone2one ENSBTAG00000004760Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]PPYR1
Tupaia_belangerione2one ENSTBEG00000012521Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Dipodomys_ordiione2one ENSDORG00000013034Neuropeptide Y receptor type 4 (NPY4-R) (NPYR-D) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:Q61041][hgnc]
Sorex_araneusone2one ENSSARG00000002146Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Rattus_norvegicusone2one ENSRNOG00000020282Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1). [Source:UniProtKB/Swiss-Prot;Acc:Q63447][hgnc]Ppyr1
Mus_musculusone2one ENSMUSG00000048337Neuropeptide Y receptor type 4 (NPY4-R) (NPYR-D) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:Q61041][hgnc]Ppyr1
Ornithorhynchus_anatinusone2one ENSOANG00000012608Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]100090352
Monodelphis_domesticaone2one ENSMODG00000025042Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Gallus_gallusone2one ENSGALG00000005923pancreatic polypeptide receptor 1 [Source:RefSeq_peptide;Acc:NP_001026726][hgnc]PPYR1
Takifugu_rubripesone2many ENSTRUG00000016504neuropeptide Y/peptide YY receptor Npy8br [Source:RefSeq_peptide;Acc:NP_001098074][hgnc]npy8br
Oryzias_latipesone2many ENSORLG00000000273Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000011489Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000002070Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Danio_rerioone2many ENSDARG00000005780neuropeptide Y/peptide YY receptor YB [Source:RefSeq_peptide;Acc:NP_571511][hgnc]npyryb
Gasterosteus_aculeatusone2one ENSGACG00000012436Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000013601Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Danio_rerioone2many ENSDARG00000043341neuropeptide Y/peptide YY receptor YA [Source:RefSeq_peptide;Acc:NP_571515][hgnc]npyrya
Takifugu_rubripesone2many ENSTRUG00000018631neuropeptide Y/peptide YY receptor [Source:RefSeq_peptide;Acc:NP_001098073][hgnc]npy8ar
Oryzias_latipesone2many ENSORLG00000014260Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Takifugu_rubripesone2many ENSTRUG00000014788neuropeptide Y/peptide YY receptor Npy4r [Source:RefSeq_peptide;Acc:NP_001098075][hgnc]npy4r
Tetraodon_nigroviridisone2many ENSTNIG00000016553Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]
Oryzias_latipesone2many ENSORLG00000009534Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) [Source:UniProtKB/Swiss-Prot;Acc:P50391][hgnc]